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Roxee Meds Catalog

Lokivetmab

Medication catalog facts with explicit FDA-approval, off-label, source-limited, and safety context.

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Data freshness

Storefront facts
Source review pending
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Roxee is still reviewing source support for this medication profile.

FDA applications
Regulatory match pending
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Roxee has safety or ingredient evidence for this medication, but a regulatory product/application match is still pending.

Safety reports
Safety data refreshed
May 5, 2026, 10:01 a.m.

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:05 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC

Evidence

Reviewed / Updated / Sources

Reviewed by: Not available

Last reviewed: April 15, 2026

Updated: April 15, 2026, 10:04 AM UTC

Sources:
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Lokivetmab

Lokivetmab

Drug type: Generic ingredient • Generic profile • Source coverage pending

Dog 85% storefront ready

Species: Dog

Approval status: Source coverage pending. Roxee has limited supporting content for this record, but no on-page official FDA animal-drug document is linked yet. Treat it as source-limited until the ETL backfill adds official coverage.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Lokivetmab

Monoclonal antibody used to reduce itch associated with atopic dermatitis in dogs. Species commonly shown: Dog.

Generic name
Lokivetmab
Species
Dog
Completeness
85%
Validation
Incomplete

Indications / Uses

Monoclonal antibody used to reduce itch associated with atopic dermatitis in dogs.

Administration / How To Give

Injectable

Storage

Refrigerate and protect from light; do not freeze.

Warnings / Contraindications

Discuss use in dogs with a history of severe allergic reactions.

  • Discuss use in dogs with a history of severe allergic reactions.

Side Effects

Injection site reactions, lethargy; generally well tolerated.

FAQ

Dog

Refrigerate and protect from light; do not freeze.

Related Medications

Cyclosporine Same category: Allergies / Itching Diphenhydramine Same category: Allergies / Itching Oclacitinib Same category: Allergies / Itching Oclacitinib Maleate Same category: Allergies / Itching Prednisone Same category: Allergies / Itching Meloxicam Same category: Allergies / Itching

Related Conditions

Atopic Dermatitis (Canine Atopy)

Source Transparency

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Used for:

Monoclonal antibody used to reduce itch associated with atopic dermatitis in dogs.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • Discuss use in dogs with a history of severe allergic reactions
  • very low energy (1 reports)
  • Pinnal ulcer (1 reports)
  • Not himself/herself (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?
Major cautions & emergency warning signs

Side effects to monitor:

  • Discuss use in dogs with a history of severe allergic reactions
  • very low energy
  • Pinnal ulcer
  • Not himself/herself

Most reported reactions:

  • Tiredness (lethargy) (1 reports)
  • Pinnal ulcer (1 reports)
  • Not himself/herself (1 reports)

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
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Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Dog
Manufacturer: Manufacturer not confirmed

Warnings / Contraindications

Discuss use in dogs with a history of severe allergic reactions.

  • High: Discuss use in dogs with a history of severe allergic reactions.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
22
Species represented
1
Grouped by Body System
Digestive (1) · Decreased appetite Skin & allergy (2) · Itching, Application site itching Neurologic (1) · Tiredness (lethargy) Other (28) · Pollakiuria, Pinnal ulcer, Not himself/herself
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Neurologic 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1

Species coverage: Dog (32)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Neurologic Dog Serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Skin & allergy Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Digestive Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Dog Non-serious - 1
Skin & allergy Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Source metadata:

Storage & Handling

Refrigerate and protect from light; do not freeze.

Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Storefront facts: Source Roxee | Refreshed May 5, 2026, 10:05 AM UTC
    The storefront fact projection used for browse cards and quick facts.
  • openFDA reaction terms: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed May 5, 2026, 10:04 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Dog
Safety (openFDA)
Top reactions: Dog 26 • Cat 0 • View
Case summaries: 6 (showing 6) • View
openFDA reports are unverified and do not prove causation.
Explore
Related conditions: Atopic Dermatitis (Canine Atopy)
Linked using: Usage_Inferred (0.78)
Diagnosis Codes
ICD10_CM: L20.9
Atopic dermatitis, unspecified

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Discuss use in dogs with a history of severe allergic reactions. (Contraindication, High)
Top reaction signals
Tiredness (lethargy) (1) Pinnal ulcer (1) Not himself/herself (1) Low platelet count (1) Loss of hearing (1) Localised oedema (1) Injection site pain (1) Inappetence (1)

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 19 Clinical 47 Manufacturer 0 Marketing 0
Current Field Facts
  • contraindications: Discuss use in dogs with a history of severe allergic reactions. (Clinical, 2026-05-05)
  • contraindications: Discuss use in dogs with a history of severe allergic reactions. (Clinical, 2026-05-03)
  • contraindications: Discuss use in dogs with a history of severe allergic reactions. (Clinical, 2026-04-30)
  • contraindications: Discuss use in dogs with a history of severe allergic reactions. (Clinical, 2026-04-29)
  • contraindications: Discuss use in dogs with a history of severe allergic reactions. (Clinical, 2026-04-28)
  • contraindications: Discuss use in dogs with a history of severe allergic reactions. (Clinical, 2026-04-27)
  • contraindications: Discuss use in dogs with a history of severe allergic reactions. (Clinical, 2026-04-26)
  • contraindications: Discuss use in dogs with a history of severe allergic reactions. (Clinical, 2026-04-25)
  • contraindications: Discuss use in dogs with a history of severe allergic reactions. (Clinical, 2026-04-17)
  • contraindications: Discuss use in dogs with a history of severe allergic reactions. (Clinical, 2026-04-15)
  • contraindications: Discuss use in dogs with a history of severe allergic reactions. (Clinical, 2026-04-15)
  • contraindications: Discuss use in dogs with a history of severe allergic reactions. (Clinical, 2026-04-11)
  • contraindications: Discuss use in dogs with a history of severe allergic reactions. (Clinical, 2026-02-12)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-21)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-20)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-19)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-17)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-16)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-16)
  • monitoring: Monitor blood glucose and ketones, hydration status, appetite, and clinical response at regular intervals. (Clinical, 2026-04-15)
Recent Revisions
  • side_effects updated 2026-05-05 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-05-05 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-05-05 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-05-03 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-05-03 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-05-03 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-30 10:09 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-30 10:09 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-30 10:09 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-29 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-29 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-29 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-28 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-28 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-28 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-27 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-27 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-27 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-26 10:06 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-26 10:06 by etl_backfill • Backfilled from existing medication fields

Usage

Monoclonal antibody used to reduce itch associated with atopic dermatitis in dogs.

Contraindications

Discuss use in dogs with a history of severe allergic reactions.

Side Effects

Injection site reactions, lethargy; generally well tolerated.

Source: FDA openFDA • Reference

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Decreased appetite (1) • Dog

Showing top 5 for Digestive.

Skin & allergy
Itching (1) • Dog Application site itching (1) • Dog

Showing top 5 for Skin & allergy.

Neurologic
Tiredness (1) • Dog

Showing top 5 for Neurologic.

Other
Pollakiuria (1) • Dog Pinnal ulcer (1) • Dog Not himself/herself (1) • Dog Low platelet count (1) • Dog Loss of hearing (1) • Dog
Show more (23)
Localised oedema (1) • Dog Injection site pain (1) • Dog Increased weight (1) • Dog Inappropriate urination (1) • Dog Inappetence (1) • Dog Impaired hearing (1) • Dog Hypocortisolaemia (1) • Dog Hearing decreased (1) • Dog Female reproductive tract disorder NOS (1) • Dog Fear/fearful (1) • Dog Elevated serum alkaline phosphatase (1) • Dog Elevated alanine aminotransferase (1) • Dog Discomfort NOS (1) • Dog Dermal mass (1) • Dog Decreased packed cell volume (1) • Dog Decreased haematocrit (1) • Dog Death (1) • Dog Deafness (1) • Dog Confusion (1) • Dog Blood in urine (1) • Dog Application site reddening (1) • Dog Application site discharge NOS (1) • Dog Abnormal adrenocorticotropic hormone (ACTH) stimulation test (1) • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Terrier - Irish Soft-coated Wheaten, Male, 12 year, 21.319 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Death • Outcome: Died

  • Report ID: USA-USFDACVM-2025-US-074219
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 12.00 Year
  • Weight: 21.319 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Death
Outcomes: Died

Dog, ['Schnauzer (unspecified)', 'Poodle - Miniature'], Female, 12 year, 11.3 kilogram • Drug: MSK, Injection, Unknown, Frequency: 1 per month • Reactions: Not himself/herself, Tiredness, Impaired hearing, Fear/fearful, Confusion • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-069675
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Female
  • Age: 12.00 Year
  • Weight: 11.300 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Injection
  • Frequency: 1 per month
Reactions Reported:
Not himself/herself Tiredness Impaired hearing Fear/fearful Confusion
Outcomes: Outcome Unknown

Dog, ['Shih Tzu', 'Dog (unknown)'], Male, 12 year, 10.7 kilogram • Drug: MSK, Injection, Unknown • Reactions: Dermal mass • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-069999
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 12.00 Year
  • Weight: 10.700 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Injection
Reactions Reported:
Dermal mass
Outcomes: Recovered/Normal

Dog, Shepherd Dog - German, Male, 9 year, 40.37 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Injection site pain, Not himself/herself, Vomiting, Wobbliness, Unexplained death • Outcome: Died

  • Report ID: USA-USFDACVM-2025-US-067552
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 9.00 Year
  • Weight: 40.370 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Injection site pain Not himself/herself Vomiting Wobbliness Unexplained death
Outcomes: Died

Dog, Havanese, Female, 12 year, 10.5 kilogram • Drug: MSK, Injection, Unknown • Reactions: Blood in urine, Hypocortisolaemia, Abnormal adrenocorticotropic hormone (ACTH) stimulation test • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-069486
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 12.00 Year
  • Weight: 10.500 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Injection
Reactions Reported:
Blood in urine Hypocortisolaemia Abnormal adrenocorticotropic hormone (ACTH) stimulation test
Outcomes: Outcome Unknown

Dog, Shepherd Dog - German, Male, 43.4 kilogram • Drug: MSK, Unknown • Reactions: Decreased appetite, Tiredness (lethargy), Inappetence, Elevated alanine aminotransferase, Elevated serum alkaline phosphatase… • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-065104
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Weight: 43.400 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Decreased appetite Tiredness (lethargy) Inappetence Elevated alanine aminotransferase Elevated serum alkaline phosphatase Decreased haematocrit Decreased packed cell volume Low platelet count Discomfort NOS Loss of hearing Localised oedema Hearing decreased
Outcomes: Outcome Unknown

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

Refrigerate and protect from light; do not freeze.

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