Roxee Medication Guide

Prednisone

Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.

Both Reference complete FDA data linked Rx required Liquid (Suspension) Intervet, Inc. Official label facts Owner quick guide first

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Data freshness

Reference facts

Reference refreshed

Aug 6, 2026, 7:46 p.m.

These are the reference facts Roxee uses on browse cards and quick facts.

FDA applications

FDA application data refreshed

Aug 6, 2026, 7:46 p.m.

Sponsor, product, and application records imported from Animal Drugs @ FDA.

Safety reports

Safety data refreshed

Aug 6, 2026, 7:49 p.m.

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details

Reference facts: Source Roxee | Refreshed Aug 6, 2026, 7:46 PM UTC
The reference fact projection used for browse cards and quick facts.
Animal Drugs @ FDA: Source FDA | Refreshed Aug 6, 2026, 7:46 PM UTC
Applications/products are imported from FDA export data.
Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
Label highlights/doc links are fetched from FDA preview endpoints.
openFDA reaction terms: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC
openFDA case summaries: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC

Illustration placeholder

Prednisone

Drug type: Generic ingredient • Generic profile • No FDA branded products linked

Both Liquid (Suspension) Rx required 100% reference complete

Species: Both

Manufacturer: Intervet, Inc.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Prednisone

Corticosteroid used for inflammatory and immune-mediated conditions. Species commonly shown: Both, Dog, Restricted During Pregnancy, Horse, Restricted During Pregnancy.

Generic name

Prednisone

Brand names

Meticorten®

Manufacturer

Intervet, Inc.

Species

Both, Dog, Horse, Cat

Dosage forms

Liquid (Suspension)

Prescription

Prescription required

Completeness

100%

Validation

Complete

Brand names

Meticorten®

Dosage forms

Liquid (Suspension)

Indications / Uses

Corticosteroid used for inflammatory and immune-mediated conditions.

Administration / How To Give

Oral

Storage

Store at room temperature.

Warnings / Contraindications

Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history.

Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history.

Side Effects

Increased thirst/urination, increased appetite, panting, GI upset. Long-term use: immune suppression and other risks.

FAQ

Both, Dog, Restricted During Pregnancy, Horse, Restricted During Pregnancy, Horse, Not For Meat Production, Cat, Restricted During Pregnancy

Yes. Roxee shows this as prescription-only.

Liquid (Suspension)

Store at room temperature.

Related Medications

Related Conditions

Dystocia Metritis

Source Transparency

Verified source: https://www.roxee.ai/meds/
Verified source: https://animaldrugsatfda.fda.gov
Verified source: https://api.fda.gov/animalandveterinary/event.json
Verified source: https://www.roxee.ai/conditions/
Last refreshed: Aug 6, 2026, 7:46 p.m.
Last verified: Feb 12, 2026, 7:40 p.m.
Validation status: Complete

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Used for:

It is used for conditions requiring an anti-inflammatory agent.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

Avoid combining with NSAIDs
Use caution with diabetes, infections, GI ulcer history
wobbly/unsteady walking (1 reports)
Loss of appetite (1 reports)
Blood in urine (1 reports)

When to call the vet:

Repeated vomiting or diarrhea.
Severe lethargy (hard to wake, very low energy).
Collapse or fainting.
Trouble breathing.
Facial swelling or hives.
Blood in vomit or stool.

What to tell or ask your vet today:

Is this medicine the right fit for my pet’s current symptoms?
Which warning signs mean I should call back right away?
How should I handle missed doses or refusal to take the medicine?

Next actions

Talk to a Vet / Find a Vet Near You Save to pet meds Share page Review report evidence

Research brief

Medication Research Insights

A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.

Source Backed Signals

What to know

Evidence-backed context Limited

Roxee has limited cited overview evidence for Prednisone; use the official documents and your veterinarian's instructions for product-specific decisions.

Source: openFDA case USA-USFDACVM-2026-US-014449

Safety signal coverage Reported signals

32 tracked reaction signals; 32 reported cases; 19 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.

Source: openFDA case USA-USFDACVM-2026-US-014449

Interpretation guardrail Not causation

Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.

Evidence tension

Stronger signal Label / review

Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.

Source: openFDA case USA-USFDACVM-2026-US-014449

Weaker signal Reported data

Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.

Reaction signal map

Most reported reactions Top terms

Unsteady walking (ataxia) (1 reports), Loss of appetite (1 reports), Blood in urine (1 reports), Blood in faeces (1 reports), Aspiration pneumonia (1 reports)

Body systems represented Signal grouping

Digestive (2), Skin & allergy (3), Neurologic (1), Behavior (2)

Explore supporting adverse reports

Species and breed lens

Species represented in reports Species lens

Dog (23 reports), Cat (9 reports)

Breed metadata in reports Metadata only

Schnauzer - Miniature (1), Chihuahua (1), ['Shepherd Dog - Australian', 'Dog (unknown)'] (1), Retriever - Labrador (1). These are report metadata, not proof that a breed is at higher risk.

What your vet may verify

Fit for this patient Vet check

Verify whether Prednisone fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.

Evidence limitations Evidence review

Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.

What to watch next

Watch list Owner-safe

Avoid combining with NSAIDs, Use caution with diabetes, infections, GI ulcer history, wobbly/unsteady walking, Loss of appetite, Blood in urine

Call sooner if Escalation

Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.

Bottom line: Use this Prednisone brief as a structured watch list and source map, not as a reason to start, stop, or change treatment without your veterinarian.

Vet source depth

openFDA case USA-USFDACVM-2026-US-014449 · adverse_reaction · adverse reactions
Contraindication source · fda_animal_drugs · warnings contraindications
FDA application profile · official_label · quick facts
Medication usage source · fda_animal_drugs · quick facts
SPL · document · documents

Evidence

Review status / Updated / Sources

Review status: Clinical reviewer not listed

Updated: February 12, 2026, 7:40 PM UTC

Sources:

FDA application profile · official_label
Medication usage source · fda_animal_drugs
openFDA case USA-USFDACVM-2026-US-014449 · adverse_reaction
SPL · document

Safety & side effects

Side effects to monitor:

Avoid combining with NSAIDs
Use caution with diabetes, infections, GI ulcer history
wobbly/unsteady walking
Loss of appetite
Blood in urine

Most reported reactions:

Unsteady walking (ataxia) (1 reports)
Loss of appetite (1 reports)
Blood in urine (1 reports)

Explore reported case details

Emergency warning signs:

Repeated vomiting or diarrhea.
Severe lethargy (hard to wake, very low energy).
Collapse or fainting.
Trouble breathing.

Talk to a Vet / Find a Vet Near You Start Symptom Intake

Vet Fast Scan

Source-backed clinical checkpoints for quick review.

FDA-labeled species

Cat, Dog, Horse

Indication / use

It is used for conditions requiring an anti-inflammatory agent.

Form / route / dose

Form: Liquid (Suspension)
Route: Intramuscular
Confirm product label and patient-specific plan.

Warnings

High: Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history.

Adverse-event caveat

openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.

Source docs

Meticorten® SPL

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both

Manufacturer: Intervet, Inc.

Form: Liquid (Suspension)

Identifiers:

NADA: 9963

Source metadata:

https://animaldrugsatfda.fda.gov/adafda/views/#/home/previewsearch/9963 · official_label · FDA application profile
https://animaldrugsatfda.fda.gov · fda_animal_drugs · Medication usage source

Warnings / Contraindications

Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history.

High: Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history.

Source metadata:

https://animaldrugsatfda.fda.gov · fda_animal_drugs · Contraindication source

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Reported case explorer

Filter stored openFDA reports by pet and report attributes. Counts describe reports in this data set, not risk.

Clear filters

openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.

Stored reports

Matching reports

Active filters

Species

Breed

Size / weight

Age

Sex

Seriousness

Outcome

Reaction

Body system

Region

Received after

Received before

Reset

Drill into common report signals

Lethargy (see also Central nervous system depression in Neurological) (16) Lack of efficacy - NOS (11) Weight loss (9) Not eating (8) Other (59) Neurologic (25) Digestive (22) Skin & allergy (18)

Showing up to 50 matching reports. Narrow filters to inspect the remaining reports.

USA-USFDACVM-2026-US-014449

Received 2026-03-25 · MSK · MSK

Serious

Species: Dog
Breed: Schnauzer - Miniature
Size / weight: 10-24 lb (10.16 Kilogram)
Age: 4-7 years (5 Year)
Sex: Male Neutered
Region: USA
Reactions: LamenessWobblinessLethargy (see also Central nervous system depression in Neurological)Unable to walkWeaknessFeverImmune-mediated polyarthritisGastritisAbdominal cavity disorder NOSAbnormal ultrasound findingHyperproteinaemiaLymphopeniaEosinopeniaMedication error NOS
Body systems: OtherNeurologic
Outcomes: Ongoing

USA-USFDACVM-2026-US-013826

Received 2026-03-24 · MSK · MSK

Serious

Species: Dog
Breed: Chihuahua
Size / weight: Under 10 lb (4.173 Kilogram)
Age: 8+ years (12 Year)
Sex: Female Unknown
Region: USA
Reactions: Luxation/subluxationLack of efficacy - NOSJoint swellingBone and joint disorder NOSPain NOSLamenessHyperextension
Body systems: OtherEffectivenessSkin & allergy
Outcomes: Ongoing

USA-USFDACVM-2026-US-013823

Received 2026-03-24 · MSK · MSK

Serious

Species: Dog
Breed: ['Shepherd Dog - Australian', 'Dog (unknown)']
Size / weight: 50-99 lb (41.05 Kilogram)
Age: 8+ years (10.4 Year)
Sex: Male Neutered
Region: USA
Reactions: Lack of efficacy - NOSLow thyroxine (T4)
Body systems: EffectivenessOther
Outcomes: Ongoing

USA-USFDACVM-2026-US-013484

Received 2026-03-20 · MSK · MSK

Serious

Species: Dog
Breed: Retriever - Labrador
Size / weight: 50-99 lb (28.576 Kilogram)
Age: 8+ years (1 Year)
Sex: Male Neutered
Region: USA
Reactions: LimpingLimb weaknessCoughNeurological signs NOSWobblinessCollapse NOS (see also Cardio-vascular and Neurological disorders)FeverJoint painJoint swellingGait abnormalityTense musclesElevated alanine aminotransferase (ALT)Elevated serum alkaline phosphatase (ALP)HyperglycaemiaNeutrophiliaAbnormal radiograph findingImmune-mediated polyarthritisBlood in faecesMedication error NOS
Body systems: OtherNeurologicSkin & allergy
Outcomes: Ongoing

USA-USFDACVM-2026-US-013182

Received 2026-03-20 · MSK · MSK

Serious

Species: Dog
Breed: Crossbred Canine/dog
Size / weight: 50-99 lb (28.168 Kilogram)
Age: 8+ years (12 Year)
Sex: Male Neutered
Region: USA
Reactions: VocalisationHind limb ataxiaInappropriate defecationBehavioural disorder NOSMuscle stiffnessInjection site pain
Body systems: OtherNeurologicBehavior
Outcomes: Ongoing

USA-USFDACVM-2026-US-014481

Received 2026-03-19 · MSK · MSK

Serious

Species: Dog
Breed: Poodle - Standard
Size / weight: 25-49 lb (18.552 Kilogram)
Age: 4-7 years (6 Year)
Sex: Female Unknown
Region: USA
Reactions: DroolingNauseaInjection site swelling
Body systems: DigestiveSkin & allergy
Outcomes: Ongoing

USA-USFDACVM-2026-US-014254

Received 2026-03-19 · MSK · MSK

Serious

Species: Dog
Breed: Pit Bull
Age: 8+ years (8.58 Year)
Sex: Female Neutered
Region: USA
Reactions: CoughDeath by euthanasiaLow platelet countPulmonary oedemaCoughing up bloodRespiratory distress
Body systems: Other
Outcomes: Euthanized

USA-USFDACVM-2026-US-013216

Received 2026-03-19 · MSK · MSK

Serious

Species: Dog
Breed: Shepherd Dog - Australian
Size / weight: 50-99 lb (25.85 Kilogram)
Age: 4-7 years (5.83 Year)
Sex: Male Neutered
Region: USA
Reactions: Partial lack of efficacySkin lesion NOSInappropriate elimination NOSPolyuriaPolydipsiaMedication error NOSLickingAbnormal histology NOS
Body systems: EffectivenessOther
Outcomes: Ongoing

USA-USFDACVM-2026-US-012895

Received 2026-03-19 · MSK · MSK

Serious

Species: Dog
Breed: Shepherd Dog - German
Size / weight: 50-99 lb (30.844 Kilogram)
Age: 4-7 years (4 Year)
Sex: Female Unknown
Region: USA
Reactions: Injection site painInjection site swellingEmesis (multiple)Decreased appetitePica NOSLocalised pain NOS (see other SOCs for specific pain)Eosinophilia
Body systems: OtherSkin & allergyDigestive
Outcomes: Ongoing

USA-USFDACVM-2026-US-013220

Received 2026-03-17 · MSK · MSK

Non-serious

Species: Dog
Breed: ['Terrier - Bull - American Pit', 'Dog (unknown)']
Age: 8+ years (13 Year)
Sex: Male Neutered
Region: USA
Reactions: Head downWalking difficulty
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2026-US-012782

Received 2026-03-17 · MSK · MSK

Serious

Species: Dog
Breed: Setter - English
Size / weight: 25-49 lb (21.772 Kilogram)
Age: 8+ years (9 Year)
Sex: Male Neutered
Region: USA
Reactions: Dilated renal pelvisIntestinal thickeningAbnormal ultrasound findingBradycardiaPale mucous membraneDiarrhoeaWeight lossLethargy (see also Central nervous system depression in Neurological)LymphomaMedication error NOS
Body systems: OtherDigestiveNeurologic
Outcomes: Ongoing

USA-USFDACVM-2026-US-012631

Received 2026-03-16 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Longhair
Size / weight: Under 10 lb (3.81 Kilogram)
Age: 8+ years (13 Year)
Sex: Female Unknown
Region: USA
Reactions: Emesis (multiple)VocalisationJoint ligament disorder NOS
Body systems: DigestiveOther
Outcomes: Ongoing

USA-USFDACVM-2026-US-012606

Received 2026-03-16 · MSK · MSK

Non-serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (6.98 Kilogram)
Age: 4-7 years (7 Year)
Sex: Male Neutered
Region: USA
Reactions: PruritusSkin irritationNeutropeniaElevated liver enzymes NOSLeukopenia NOS
Body systems: Skin & allergyOther
Outcomes: Outcome Unknown

USA-USFDACVM-2026-US-012110

Received 2026-03-16 · MSK · MSK

Non-serious

Species: Dog
Breed: Shar Pei
Size / weight: 50-99 lb (32.7 Kilogram)
Age: 8+ years (11 Year)
Sex: Female Neutered
Region: USA
Reactions: ArthritisDecreased appetiteHigh sodium-potassium ratio (Na:K ratio)VomitingDiarrhoeaGait abnormalityAppetite disorder NOSStiffness NOSNot defecatingWeight lossDysorexiaHair loss NOSWeaknessMuscle wastingDistension of abdomenPolyuriaDehydrationShakingShiveringTremorGreasy skinHair sheddingAnxiety
Body systems: OtherDigestiveSkin & allergyNeurologicBehavior
Outcomes: Recovered/Normal

USA-USFDACVM-2026-US-012107

Received 2026-03-16 · MSK · MSK

Non-serious

Species: Dog
Breed: Retriever - Labrador
Size / weight: 50-99 lb (33 Kilogram)
Age: 1-3 years (18 Month)
Sex: Female Intact
Region: USA
Reactions: Ear infection NOSDermatitisAbnormal cytologyOther abnormal test result NOSLack of efficacy (endoparasite) - heartworm
Body systems: OtherEffectiveness
Outcomes: Ongoing

USA-USFDACVM-2026-US-013912

Received 2026-03-13 · MSK · MSK

Serious

Species: Dog
Breed: Pointing Dog - German Short-haired
Size / weight: 50-99 lb (24.64 Kilogram)
Age: 1-3 years (2 Year)
Sex: Male Neutered
Region: USA
Reactions: CoughMegaoesophagusDecreased red blood cell countHyponatremiaHypochloraemiaLeukocytosis NOSNeutrophiliaMonocytosisHyperproteinaemiaHyperalbuminaemiaElevated globulinsIncreased urine concentrationProteinuriaEosinophiliaIncreased percentage reticulocytesHigh sodium-potassium ratio (Na:K ratio)Skin lesion NOS
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2026-US-011996

Received 2026-03-13 · MSK · MSK

Serious

Species: Dog
Breed: Terrier - Bull - American Pit
Size / weight: 50-99 lb (29.937 Kilogram)
Age: 4-7 years (5 Year)
Sex: Male Neutered
Region: USA
Reactions: Injection site painAnorexiaFeverInjection site swellingInjection site abscessLethargy (see also Central nervous system depression in Neurological)
Body systems: OtherDigestiveSkin & allergyNeurologic
Outcomes: Ongoing

USA-USFDACVM-2026-US-012599

Received 2026-03-12 · MSK · MSK

Serious

Species: Dog
Breed: Bulldog - English
Size / weight: 50-99 lb (22.68 Kilogram)
Age: 4-7 years (4 Year)
Sex: Female Neutered
Region: USA
Reactions: Head tremorFly biting behaviourLack of efficacy - NOSPolydipsiaPruritusPolyuriaPyodermaElevated blood urea nitrogen (BUN)Urinary tract infectionProteinuriaHaematuria
Body systems: NeurologicBehaviorEffectivenessOtherSkin & allergy
Outcomes: Outcome Unknown

USA-USFDACVM-2026-US-014477

Received 2026-03-11 · MSK · MSK

Serious

Species: Dog
Breed: Dog (unknown)
Sex: Unknown Unknown
Region: USA
Reactions: Injection site pain
Body systems: Other
Outcomes: Outcome Unknown

USA-USFDACVM-2026-US-011901

Received 2026-03-11 · MSK · MSK

Non-serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (9.253 Kilogram)
Age: 8+ years (12 Year)
Sex: Male Neutered
Region: USA
Reactions: Peripheral neuropathyPlantigrade posture
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2026-US-011045

Received 2026-03-11 · MSK · MSK

Non-serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (6.75 Kilogram)
Age: 8+ years (12 Year)
Sex: Female Neutered
Region: USA
Reactions: Inappropriate urinationHyperproteinaemiaLymphopeniaInappropriate defecationDecreased haematocritNeutrophiliaVomiting
Body systems: OtherDigestive
Outcomes: Ongoing

USA-USFDACVM-2026-US-010329

Received 2026-03-04 · MSK · MSK

Non-serious

Species: Dog
Breed: ['Shih Tzu', 'Dog (unknown)']
Size / weight: 10-24 lb (10.16 Kilogram)
Age: 8+ years (13 Year)
Sex: Female Unknown
Region: USA
Reactions: EmesisLack of efficacy - NOS
Body systems: DigestiveEffectiveness
Outcomes: Ongoing

USA-USFDACVM-2026-US-009489

Received 2026-03-02 · MSK · MSK

Non-serious

Species: Dog
Breed: Chihuahua
Size / weight: Under 10 lb (3.6 Kilogram)
Age: 8+ years (17 Year)
Sex: Male Neutered
Region: USA
Reactions: Weight loss
Body systems: Other
Outcomes: Outcome Unknown

USA-USFDACVM-2026-US-009056

Received 2026-02-26 · MSK · MSK

Serious

Species: Dog
Breed: Terrier - Bull - American Pit
Size / weight: 50-99 lb (28.49 Kilogram)
Age: 8+ years (8.42 Year)
Sex: Female Unknown
Region: USA
Reactions: Weight lossLethargy (see also Central nervous system depression in Neurological)Limb weakness
Body systems: OtherNeurologic
Outcomes: Ongoing

USA-USFDACVM-2026-US-008852

Received 2026-02-26 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (4.672 Kilogram)
Age: 8+ years (16.4 Year)
Sex: Female Unknown
Region: USA
Reactions: Diarrhoea
Body systems: Digestive
Outcomes: Ongoing

USA-USFDACVM-2026-US-008762

Received 2026-02-19 · MSK · MSK

Serious

Species: Dog
Breed: ['Retriever - Labrador', 'Crossbred Canine/dog']
Age: 1-3 years (2.25 Year)
Sex: Male Neutered
Region: USA
Reactions: DiarrhoeaLack of efficacy (endoparasite) - heartwormOtitis NOSCystitisCrustPruritus
Body systems: DigestiveEffectivenessOtherSkin & allergy
Outcomes: Outcome Unknown

USA-USFDACVM-2026-US-010643

Received 2026-02-12 · MSK · MSK

Non-serious

Species: Dog
Breed: Retriever - Golden
Size / weight: 50-99 lb (30.844 Kilogram)
Age: 4-7 years (6 Year)
Sex: Female Unknown
Region: USA
Reactions: Localised pain NOS (see other SOCs for specific pain)Limb non-weight bearingSwollen limbWhiningUncomfortablePain NOSReluctant to moveInappropriate urinationAbnormal urine odourInjection site bleedingAnorexiaInjection site itchingInjection site irritationInjection site self traumaLimpingInjection site discharge NOSSkin irritationReddening of the skinAlopecia localInjection site scratchingInjection site swellingInjection site hair loss
Body systems: OtherDigestiveSkin & allergy
Outcomes: Outcome Unknown

USA-USFDACVM-2026-US-006203

Received 2026-02-10 · MSK · MSK

Serious

Species: Dog
Breed: Mountain Dog - Bernese
Size / weight: 50-99 lb (35.698 Kilogram)
Age: 4-7 years (7 Year)
Sex: Female Unknown
Region: USA
Reactions: Lethargy (see also Central nervous system depression in Neurological)InappetenceSwollen lip (see also Skin)Localised pain NOS (see other SOCs for specific pain)Ocular dischargeNot drinkingSmelly breathLip smackingWalking difficultyAbdominal painDrooping eyelidReluctant to moveOral ulcerationTongue ulcerationIntentional misuse
Body systems: NeurologicOther
Outcomes: Ongoing

USA-USFDACVM-2026-US-005003

Received 2026-02-04 · MSK · MSK

Serious

Species: Dog
Breed: Rottweiler
Size / weight: 50-99 lb (4 Kilogram)
Age: 8+ years (1 Year)
Sex: Female Unknown
Region: USA
Reactions: Addison's diseaseLethargy (see also Central nervous system depression in Neurological)FebrileDecreased pulse oxygenationAspiration pneumoniaHypotensionElevated lactateHind limb paresisReduced reflexesDeath
Body systems: OtherNeurologic
Outcomes: Died

USA-USFDACVM-2026-US-005573

Received 2026-01-30 · MSK · MSK

Non-serious

Species: Dog
Breed: ['Retriever - Labrador', 'Chow Chow']
Size / weight: 50-99 lb (24.95 Kilogram)
Age: 4-7 years (5 Year)
Sex: Female Neutered
Region: USA
Reactions: Localised oedema (not application site)WoundSwollen limbLickingLocalised pain NOS (see other SOCs for specific pain)Tooth disorder
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2025-US-075439

Received 2025-12-29 · MSK · MSK

Serious

Species: Dog
Breed: ['Corgi - Welsh Cardigan', 'Chihuahua']
Size / weight: Under 10 lb (4.5 Kilogram)
Age: 8+ years (13 Year)
Sex: Male Neutered
Region: USA
Reactions: Loss of hearingLack of efficacy - NOS
Body systems: OtherEffectiveness
Outcomes: Recovered with Sequela

USA-USFDACVM-2025-US-075299

Received 2025-12-29 · MSK · MSK

Non-serious

Species: Cat
Breed: Domestic Shorthair
Sex: Male Unknown
Region: USA
Reactions: Not eatingBalance impairedApplication site hair lossApplication site scab
Body systems: OtherSkin & allergy
Outcomes: Recovered/Normal

USA-USFDACVM-2025-US-075064

Received 2025-12-23 · MSK · MSK

Non-serious

Species: Dog
Breed: Terrier - Boston
Size / weight: 10-24 lb (8.16 Kilogram)
Age: 1-3 years (2 Year)
Sex: Female Neutered
Region: USA
Reactions: RashAlopecia
Body systems: Skin & allergy
Outcomes: Ongoing

USA-USFDACVM-2025-US-075291

Received 2025-12-22 · MSK · MSK

Serious

Species: Dog
Breed: Shepherd Dog - German
Size / weight: 50-99 lb (44.45 Kilogram)
Age: 8+ years (10.9 Year)
Sex: Female Unknown
Region: USA
Reactions: Lack of efficacy - NOSSeizure NOSOther abnormal test result NOSAtaxiaMusculoskeletal disorder NOSElevated serum alkaline phosphatase (ALP)
Body systems: EffectivenessNeurologicOther
Outcomes: Ongoing

USA-USFDACVM-2025-US-074895

Received 2025-12-19 · MSK · MSK

Serious

Species: Dog
Breed: Bloodhound
Size / weight: 50-99 lb (41.28 Kilogram)
Age: 4-7 years (5 Year)
Sex: Female Neutered
Region: USA
Reactions: Lethargy (see also Central nervous system depression in Neurological)Stiffness NOSWalking difficultyGeneralised weaknessNeutropeniaLow platelet countPain NOSDecreased appetiteVomitingElevated liver enzymes NOSFluid in abdomen NOSLiver disorder NOSOther immune system disorder NOSFeverLeucopenia NOSDistension of abdomenHypoglycaemiaAnaemia NOSIndigestion
Body systems: NeurologicOtherDigestive
Outcomes: Ongoing

USA-USFDACVM-2025-US-074702

Received 2025-12-19 · MSK · MSK

Non-serious

Species: Dog
Breed: Spaniel - King Charles Cavalier
Age: 4-7 years (6.5 Year)
Sex: Male Neutered
Region: USA
Reactions: Inflammatory bowel disorderAtopic allergy NOS (see also Skin)Allergic skin reactionBlepharitis
Body systems: Other
Outcomes: Outcome Unknown

CAN-USFDACVM-2025-CA-000113

Received 2025-12-19 · MSK · MSK

Non-serious

Species: Dog
Breed: ['Siberian Husky', 'Dog (unknown)']
Size / weight: 25-49 lb (22 Kilogram)
Age: 1-3 years (2 Year)
Sex: Male Intact
Region: USA
Reactions: Diarrhoea
Body systems: Digestive
Outcomes: Recovered/Normal

USA-USFDACVM-2025-US-075314

Received 2025-12-18 · MSK · MSK

Serious

Species: Dog
Breed: ['Crossbred Canine/dog', 'Chihuahua']
Size / weight: 10-24 lb (6.36 Kilogram)
Age: 8+ years (1 Year)
Sex: Female Neutered
Region: USA
Reactions: DehydrationFeverDecreased appetite
Body systems: OtherDigestive
Outcomes: Ongoing

USA-USFDACVM-2025-US-075336

Received 2025-12-17 · MSK · MSK

Serious

Species: Dog
Breed: Chihuahua
Size / weight: Under 10 lb (2.54 Kilogram)
Age: 8+ years (15.5 Year)
Sex: Female Unknown
Region: USA
Reactions: SyncopeInvoluntary defecationDecreased body temperatureLymphopeniaThrombocytosisElevated serum alkaline phosphatase (ALP)Medication error NOSPulmonary hypertension
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2025-US-075245

Received 2025-12-16 · MSK · MSK

Serious

Species: Dog
Breed: Retriever - Golden
Size / weight: 10-24 lb (6.622 Kilogram)
Age: Under 1 year (2 Month)
Sex: Male Intact
Region: USA
Reactions: WeaknessNot eatingLying downInappropriate urinationDifficulty standingWalking slowlyCollapse NOS (see also Cardio-vascular and Neurological disorders)Pain NOSSneezingCough, productiveInvoluntary urinationUnable to walkLeucocytosis NOSAnaemia NOSDecreased blood urea nitrogen (BUN) or creatinineAbdominal painGastric ulcerSeizure NOSDeathLack of efficacy - NOS
Body systems: OtherNeurologicEffectiveness
Outcomes: Died

USA-USFDACVM-2025-US-073483

Received 2025-12-15 · MSK · MSK

Non-serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: Under 10 lb (4.44 Kilogram)
Age: 1-3 years (2.33 Year)
Sex: Female Neutered
Region: USA
Reactions: Emesis (multiple)
Body systems: Digestive
Outcomes: Outcome Unknown

USA-USFDACVM-2025-US-072787

Received 2025-12-15 · MSK · MSK

Serious

Species: Dog
Breed: Poodle - Standard
Size / weight: 25-49 lb (20.412 Kilogram)
Age: 1-3 years (2 Year)
Sex: Female Intact
Region: USA
Reactions: Death by euthanasiaConjunctivitisUlceration NOSEar canal erythemaWeltBumps on skinSkin inflammation NOSAnorexiaPain NOSDifficulty to risePyodermaAbnormal histology NOSSeizure NOSNeutropeniaMonocytosisElevated creatinineThrombocytopeniaHyperkeratosisPruritus
Body systems: OtherDigestiveNeurologicSkin & allergy
Outcomes: Euthanized

USA-USFDACVM-2025-US-074897

Received 2025-12-12 · MSK · MSK

Serious

Species: Dog
Breed: ['Chihuahua', 'Dog (unknown)']
Size / weight: Under 10 lb (2.26 Kilogram)
Age: Under 1 year (2 Week)
Sex: Female Intact
Region: USA
Reactions: IcterusDeathOther abnormal test result NOSElevated liver enzymes NOSSwollen jointLocalised hair lossSkin lesion NOSConjunctival oedemaCorneal oedemaSkin scabSwollen limbLethargy (see also Central nervous system depression in Neurological)AnorexiaEar infection NOSLocal swelling (not application site)
Body systems: OtherSkin & allergyNeurologicDigestive
Outcomes: Died

USA-USFDACVM-2025-US-074521

Received 2025-12-11 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Longhair
Size / weight: 10-24 lb (6.4 Kilogram)
Age: 4-7 years (6 Year)
Sex: Male Neutered
Region: USA
Reactions: Lethargy (see also Central nervous system depression in Neurological)TremorAtaxiaLaboured breathingAgonal breathingLateral recumbencyShallow breathingAbnormal menace reflex testAbnormal pupil light reflexHead tilt - neurological disorder (see also Head tilt - ear disorder)Other abnormal test result NOS
Body systems: NeurologicOther
Outcomes: Ongoing

USA-USFDACVM-2025-US-072505

Received 2025-12-11 · MSK · MSK

Serious

Species: Dog
Breed: Terrier - Bull - Staffordshire
Size / weight: 50-99 lb (30.935 Kilogram)
Age: 4-7 years (4 Year)
Sex: Female Neutered
Region: USA
Reactions: EmesisRegurgitationNauseaGastric distensionMedication error NOSAbnormal radiograph finding
Body systems: DigestiveOther
Outcomes: Ongoing

USA-USFDACVM-2025-US-072814

Received 2025-12-10 · MSK · MSK

Serious

Species: Dog
Breed: Pinscher - Miniature
Size / weight: Under 10 lb (4.037 Kilogram)
Age: 8+ years (1 Year)
Sex: Female Unknown
Region: USA
Reactions: Lethargy (see also Central nervous system depression in Neurological)TremblingLimpingHead downWalking difficultyFeverLack of efficacy - NOSElevated globulinsBlood in urineImmune-mediated polyarthropathyElevated protein:creatinine ratioProteinuriaIntentional misuse
Body systems: NeurologicOtherEffectiveness
Outcomes: Ongoing

USA-USFDACVM-2025-US-073819

Received 2025-12-09 · MSK · MSK

Serious

Species: Dog
Breed: Crossbred Canine/dog
Size / weight: 50-99 lb (26.49 Kilogram)
Age: 8+ years (12 Year)
Sex: Female Neutered
Region: USA
Reactions: UnwellNot eatingWoundDeathNecropsy performed
Body systems: Other
Outcomes: Died

USA-USFDACVM-2025-US-072289

Received 2025-12-08 · MSK · MSK

Non-serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: Under 10 lb (3.62 Kilogram)
Age: 4-7 years (7 Year)
Sex: Female Neutered
Region: USA
Reactions: UnwellWeight lossLethargy (see also Central nervous system depression in Neurological)HypoglycaemiaNot eating
Body systems: OtherNeurologic
Outcomes: Outcome Unknown

USA-USFDACVM-2025-US-073462

Received 2025-12-04 · MSK · MSK

Serious

Species: Dog
Breed: Corgi - Welsh Cardigan
Size / weight: 10-24 lb (11.07 Kilogram)
Age: 4-7 years (5 Year)
Sex: Male Neutered
Region: USA
Reactions: Loose stoolDigestive tract disorder NOSHigh sodium-potassium ratio (Na:K ratio)Abnormal cytologyDiarrhoeaShakingAnorexiaNot himself/herselfIncreased drinkingHyperglycaemiaElevated serum alkaline phosphatase (ALP)NeutrophiliaLymphopenia
Body systems: OtherDigestive
Outcomes: Outcome Unknown

USA-USFDACVM-2025-US-071810

Received 2025-12-02 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (5.761 Kilogram)
Age: 8+ years (1 Year)
Sex: Female Unknown
Region: USA
Reactions: Breathing difficultyWheezingSneezing
Body systems: Other
Outcomes: Ongoing

Tap or hover a reaction to see what it means in plain language.

Tracked signals

Reported cases

Serious reports

Species represented

Grouped by Body System

Digestive (2) · Loss of appetite, Appetite disorder NOS Skin & allergy (3) · Hair loss, Application site hair loss, Alopecia local Neurologic (1) · Unsteady walking (ataxia) Behavior (2) · Behavioral disorder (unspecified), Anxiety Other (24) · Blood in urine, Blood in faeces, Blepharitis

Most Reported Reactions

Body system	Cases	Species	Serious cases
Neurologic	1	Dog	1
Digestive	1	Dog	1
Other	1	Dog	1
Other	1	Dog	1
Other	1	Dog	1
Other	1	Dog	1
Other	1	Dog	1
Other	1	Dog	1

Species coverage: Dog (23) Cat (9)

View detailed reaction table

Body system	Species	Seriousness	Frequency	Reports
Neurologic	Dog	Serious	-	1
Digestive	Dog	Serious	-	1
Skin & allergy	Dog	Non-serious	-	1
Other	Dog	Serious	-	1
Other	Dog	Serious	-	1
Other	Dog	Non-serious	-	1
Behavior	Cat	Non-serious	-	1
Other	Cat	Non-serious	-	1
Other	Dog	Non-serious	-	1
Other	Dog	Serious	-	1
Other	Dog	Non-serious	-	1
Other	Cat	Non-serious	-	1
Skin & allergy	Cat	Non-serious	-	1
Other	Dog	Serious	-	1
Digestive	Dog	Non-serious	-	1
Behavior	Dog	Non-serious	-	1
Other	Dog	Serious	-	1
Other	Dog	Serious	-	1
Skin & allergy	Dog	Non-serious	-	1
Other	Dog	Non-serious	-	1
Other	Cat	Serious	-	1
Other	Dog	Serious	-	1
Other	Dog	Non-serious	-	1
Other	Dog	Serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Serious	-	1
Other	Cat	Serious	-	1
Other	Dog	Serious	-	1
Other	Dog	Serious	-	1
Other	Dog	Serious	-	1
Other	Cat	Serious	-	1
Other	Dog	Serious	-	1

Source metadata:

https://api.fda.gov/animalandveterinary/event.json · adverse_reaction · openFDA case USA-USFDACVM-2026-US-014449

Storage & Handling

Store at room temperature.

Source Documents

The most useful source links appear first; full previews and metadata stay in the veterinary/professional layer.

Use original documents to confirm product-specific warnings, ingredients, and handling details with your veterinarian.

Meticorten® SPL · SPL

Full source previews and metadata remain in the veterinary/professional layer.

Owner handouts

No owner handouts linked yet.

Official label / PI

No official label or package insert links yet.

SPL

FOI

No FOI links yet.

Meticorten®

SPL · SPL

Open original

FDA Structured Product Label

Meticorten®

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor: Intervet, Inc.
NADA: 9963
Status: RX
Form: Liquid (Suspension)
Route: Intramuscular
Species: Dog • Horse • Cat

Composition / specifications

Each milliliter of sterile aqueous suspension contains 10 to 40 milligrams of prednisone.

Horses

Indication

It is used for conditions requiring an anti-inflammatory agent.

Dosage

100 to 400 milligrams intramuscularly, repeating if necessary. If no response is observed after 3 to 4 days of therapy, reevaluate diagnosis.

Limitations

Do not use in viral infections. Except in emergency therapy, do not use in animals with tuberculosis, chronic nephritis, or Cushings's disease. With infections, use appropriate antibacterial therapy with and for at least 3 days after discontinuance of use and disappearance of all signs of infection. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta and metritis. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Dogs

Indication

It is used for conditions requiring an anti-inflammatory agent.

Dosage

0.25 to 1.0 milligram per pound of body weight for 3 to 5 days or until a response is noted. Treatment may be continued with an orally administered dose.

Limitations

Cats

Indication

It is used for conditions requiring an anti-inflammatory agent.

Dosage

0.25 to 1.0 milligram per pound of body weight for 3 to 5 days or until a response is noted. Treatment may be continued with an orally administered dose.

Limitations

Source metadata:

https://animaldrugsatfda.fda.gov/adafda/app/search/public/spl/file/625/Meticorten%C2%AE · document · SPL

Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness

Reference facts: Source Roxee | Refreshed Aug 6, 2026, 7:46 PM UTC
The reference fact projection used for browse cards and quick facts.
Animal Drugs @ FDA: Source FDA | Refreshed Aug 6, 2026, 7:46 PM UTC
Applications/products are imported from FDA export data.
Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
Label highlights/doc links are fetched from FDA preview endpoints.
openFDA reaction terms: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC
openFDA case summaries: Source FDA openFDA | Refreshed Aug 6, 2026, 7:52 PM UTC

Official (FDA)

Identity: Generic ingredient • No FDA branded products linked

No official FDA brand rows linked yet for this ingredient.

Case-reported brands (openFDA): MSK

Catalog species: Both • FDA-labeled species: Cat, Dog, Horse

Rx/OTC: RX

Form/route: Liquid (Suspension) • Intramuscular

Applications: NADA 9963

Documents: • SPL: 1 • Label highlights • Official documents

Safety (openFDA)

Top reactions: Dog 260 • Cat 70 • View

Case summaries: 66 (showing 8) • View

openFDA reports are unverified and do not prove causation.

Explore

Related conditions: Dystocia Metritis

Linked using: Fda_Label (0.95), Fda_Label (0.95)

Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points

Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history. (Contraindication, High)

Top reaction signals

Unsteady walking (ataxia) (1) Loss of appetite (1) Blood in urine (1) Blood in faeces (1) Aspiration pneumonia (1) Application site dry skin (1) Anaphylaxis (1) Anaemia NOS (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers

NADA: 9963

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 8 Clinical 4 Manufacturer 0 Marketing 0

Current Field Facts

side_effects: Increased thirst/urination, increased appetite, panting, GI upset. Long-term use: immune suppression and other risks. (Clinical, 2026-04-11)
storage_handling: Store at room temperature. (Clinical, 2026-04-12)
storage_handling: Store at room temperature. (Clinical, 2026-04-11)
storage_handling: Store at room temperature. (Clinical, 2026-02-12)
contraindications: Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history. (Official, 2026-04-12)
contraindications: Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history. (Official, 2026-04-11)
contraindications: Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history. (Official, 2026-02-12)
side_effects: Increased thirst/urination, increased appetite, panting, GI upset. Long-term use: immune suppression and other risks. (Official, 2026-04-12)
side_effects: Increased thirst/urination, increased appetite, panting, GI upset. Long-term use: immune suppression and other risks. (Official, 2026-02-12)
usage: Corticosteroid used for inflammatory and immune-mediated conditions. (Official, 2026-04-12)
usage: Corticosteroid used for inflammatory and immune-mediated conditions. (Official, 2026-04-11)
usage: Corticosteroid used for inflammatory and immune-mediated conditions. (Official, 2026-02-12)

Recent Revisions

side_effects updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
contraindications updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
usage updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
side_effects updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
contraindications updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
usage updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
side_effects updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
contraindications updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
usage updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product	Sponsor	Application	Status	Published
Meticorten® RX Prednisone Liquid (Suspension) • Intramuscular Label highlights Official documents	Intervet, Inc.	NADA 9963	Approved	Jun 1, 2016

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Dog • Horse • Cat

Composition / specifications

Each milliliter of sterile aqueous suspension contains 10 to 40 milligrams of prednisone.

Horses

Indication

It is used for conditions requiring an anti-inflammatory agent.

Dosage

100 to 400 milligrams intramuscularly, repeating if necessary. If no response is observed after 3 to 4 days of therapy, reevaluate diagnosis.

Limitations

Dogs

Indication

It is used for conditions requiring an anti-inflammatory agent.

Dosage

0.25 to 1.0 milligram per pound of body weight for 3 to 5 days or until a response is noted. Treatment may be continued with an orally administered dose.

Limitations

Cats

Indication

It is used for conditions requiring an anti-inflammatory agent.

Dosage

0.25 to 1.0 milligram per pound of body weight for 3 to 5 days or until a response is noted. Treatment may be continued with an orally administered dose.

Limitations

FDA page: Open in Animal Drugs @ FDA

Usage

Corticosteroid used for inflammatory and immune-mediated conditions.

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history.

Side Effects

Increased thirst/urination, increased appetite, panting, GI upset. Long-term use: immune suppression and other risks.

Source: FDA openFDA • Reference

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive

Loss of appetite (1) • Dog Appetite disorder NOS (1) • Dog

Showing top 5 for Digestive.

Skin & allergy

Hair loss (1) • Dog Application site hair loss (1) • Cat Alopecia local (1) • Dog

Showing top 5 for Skin & allergy.

Neurologic

Unsteady walking (1) • Dog

Showing top 5 for Neurologic.

Behavior

Behavioral disorder (1) • Cat Anxiety (1) • Dog

Showing top 5 for Behavior.

Other

Blood in urine (1) • Dog Blood in faeces (1) • Dog Blepharitis (1) • Dog Balance impaired (1) • Cat Atopic allergy NOS (1) • Dog

Show more (19)

Aspiration pneumonia (1) • Dog Arthritis (1) • Dog Application site scab (1) • Cat Application site dry skin (1) • Dog Anaphylaxis (1) • Dog Anaemia NOS (1) • Dog Allergic skin reaction (1) • Dog Agonal breathing (1) • Cat Addison's disease (1) • Dog Abnormal urine odour (1) • Dog Abnormal ultrasound finding (1) • Dog Abnormal radiograph finding (1) • Cat Abnormal pupil light reflex (1) • Cat Abnormal menace reflex test (1) • Cat Abnormal histology NOS (1) • Dog Abnormal cytology (1) • Dog Abdominal pain (1) • Dog Abdominal oedema (1) • Cat Abdominal cavity disorder NOS (1) • Dog

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Schnauzer - Miniature, Male, 5 year, 10.16 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Lameness, Wobbliness, Tiredness (lethargy), Unable to walk, Weakness… • Outcome: Ongoing

Report ID: USA-USFDACVM-2026-US-014449
Serious AE: Yes
Treated For AE: Yes
Sex: Male
Age: 5.00 Year
Weight: 10.160 Kilogram

Case-reported brand: MSK
Case-reported manufacturer: MSK
Route: Oral
Form: Unassigned

Reactions Reported:

Lameness Wobbliness Tiredness (lethargy) Unable to walk Weakness Fever Immune-mediated polyarthritis Gastritis Abdominal cavity disorder NOS Abnormal ultrasound finding Hyperproteinaemia Lymphopenia Eosinopenia Medication error NOS

Outcomes: Ongoing

Dog, Chihuahua, Female, 12 year, 4.173 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Luxation/subluxation, Lack of efficacy - NOS, Joint swelling, Bone and joint disorder NOS, Pain NOS… • Outcome: Ongoing

Report ID: USA-USFDACVM-2026-US-013826
Serious AE: Yes
Treated For AE: Yes
Sex: Female
Age: 12.00 Year
Weight: 4.173 Kilogram

Case-reported brand: MSK
Case-reported manufacturer: MSK
Route: Oral
Form: Unassigned

Reactions Reported:

Luxation/subluxation Lack of efficacy - NOS Joint swelling Bone and joint disorder NOS Pain NOS Lameness Hyperextension

Outcomes: Ongoing

Dog, ['Shepherd Dog - Australian', 'Dog (unknown)'], Male, 10.4 year, 41.05 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Lack of efficacy - NOS, Low thyroxine • Outcome: Ongoing

Report ID: USA-USFDACVM-2026-US-013823
Serious AE: Yes
Treated For AE: Yes
Sex: Male
Age: 10.40 Year
Weight: 41.050 Kilogram

Case-reported brand: MSK
Case-reported manufacturer: MSK
Route: Oral
Form: Unassigned

Reactions Reported:

Lack of efficacy - NOS Low thyroxine

Outcomes: Ongoing

Dog, Retriever - Labrador, Male, 10 year, 28.576 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Limping, Limb weakness, Cough, Neurological signs NOS, Wobbliness… • Outcome: Ongoing

Report ID: USA-USFDACVM-2026-US-013484
Serious AE: Yes
Treated For AE: Yes
Sex: Male
Age: 10.00 Year
Weight: 28.576 Kilogram

Case-reported brand: MSK
Case-reported manufacturer: MSK
Route: Unknown
Form: Unassigned

Reactions Reported:

Limping Limb weakness Cough Neurological signs NOS Wobbliness Collapse NOS Fever Joint pain Joint swelling Gait abnormality Tense muscles Elevated alanine aminotransferase Elevated serum alkaline phosphatase Hyperglycaemia Neutrophilia Abnormal radiograph finding Immune-mediated polyarthritis Blood in faeces Medication error NOS

Outcomes: Ongoing

Dog, Crossbred Canine/dog, Male, 12 year, 28.168 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Vocalisation, Hind limb ataxia, Inappropriate defecation, Behavioral disorder (unspecified), Muscle stiffness… • Outcome: Ongoing

Report ID: USA-USFDACVM-2026-US-013182
Serious AE: Yes
Treated For AE: Yes
Sex: Male
Age: 12.00 Year
Weight: 28.168 Kilogram

Case-reported brand: MSK
Case-reported manufacturer: MSK
Route: Oral
Form: Unassigned

Reactions Reported:

Vocalisation Hind limb ataxia Inappropriate defecation Behavioral disorder (unspecified) Muscle stiffness Injection site pain

Outcomes: Ongoing

Dog, Poodle - Standard, Female, 6 year, 18.552 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Drooling, Nausea, Injection site swelling • Outcome: Ongoing

Report ID: USA-USFDACVM-2026-US-014481
Serious AE: Yes
Treated For AE: Yes
Sex: Female
Age: 6.00 Year
Weight: 18.552 Kilogram

Case-reported brand: MSK
Case-reported manufacturer: MSK
Route: Oral
Form: Unassigned

Reactions Reported:

Drooling Nausea Injection site swelling

Outcomes: Ongoing

Dog, Pit Bull, Female, 8.58 year • Drug: MSK, Unknown • Reactions: Cough, Death by euthanasia, Low platelet count, Pulmonary oedema, Coughing up blood… • Outcome: Euthanized

Report ID: USA-USFDACVM-2026-US-014254
Serious AE: Yes
Treated For AE: Yes
Sex: Female
Age: 8.58 Year

Case-reported brand: MSK
Case-reported manufacturer: MSK
Route: Unknown

Reactions Reported:

Cough Death by euthanasia Low platelet count Pulmonary oedema Coughing up blood Respiratory distress

Outcomes: Euthanized

Dog, Shepherd Dog - Australian, Male, 5.83 year, 25.85 kilogram • Drug: MSK, Unassigned, Oral, Dose: 9.8230 Milligram per animal, Frequency: 12 per hour • Reactions: Partial lack of efficacy, Skin lesion NOS, Inappropriate elimination NOS, Polyuria, Polydipsia… • Outcome: Ongoing

Report ID: USA-USFDACVM-2026-US-013216
Serious AE: Yes
Treated For AE: Yes
Sex: Male
Age: 5.83 Year
Weight: 25.850 Kilogram

Case-reported brand: MSK
Case-reported manufacturer: MSK
Route: Oral
Form: Unassigned
Dose: 9.8230 Milligram per animal
Frequency: 12 per hour

Reactions Reported:

Partial lack of efficacy Skin lesion NOS Inappropriate elimination NOS Polyuria Polydipsia Medication error NOS Licking Abnormal histology NOS

Outcomes: Ongoing

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

Store at room temperature.

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This medication has not been reviewed by a veterinarian yet.

Medical Disclaimer: The medication details provided on Roxee are for informational purposes only and are not a substitute for professional veterinary advice. Always consult your veterinarian about your pet's specific needs.

Prednisone

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Prednisone

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Reported case explorer

USA-USFDACVM-2026-US-014449

USA-USFDACVM-2026-US-013826

USA-USFDACVM-2026-US-013823

USA-USFDACVM-2026-US-013484

USA-USFDACVM-2026-US-013182

USA-USFDACVM-2026-US-014481

USA-USFDACVM-2026-US-014254

USA-USFDACVM-2026-US-013216

USA-USFDACVM-2026-US-012895

USA-USFDACVM-2026-US-013220

USA-USFDACVM-2026-US-012782

USA-USFDACVM-2026-US-012631

USA-USFDACVM-2026-US-012606

USA-USFDACVM-2026-US-012110

USA-USFDACVM-2026-US-012107

USA-USFDACVM-2026-US-013912

USA-USFDACVM-2026-US-011996

USA-USFDACVM-2026-US-012599

USA-USFDACVM-2026-US-014477

USA-USFDACVM-2026-US-011901

USA-USFDACVM-2026-US-011045

USA-USFDACVM-2026-US-010329

USA-USFDACVM-2026-US-009489

USA-USFDACVM-2026-US-009056

USA-USFDACVM-2026-US-008852

USA-USFDACVM-2026-US-008762

USA-USFDACVM-2026-US-010643

USA-USFDACVM-2026-US-006203

USA-USFDACVM-2026-US-005003

USA-USFDACVM-2026-US-005573

USA-USFDACVM-2025-US-075439

USA-USFDACVM-2025-US-075299

USA-USFDACVM-2025-US-075064

USA-USFDACVM-2025-US-075291

USA-USFDACVM-2025-US-074895

USA-USFDACVM-2025-US-074702

CAN-USFDACVM-2025-CA-000113

USA-USFDACVM-2025-US-075314

USA-USFDACVM-2025-US-075336

USA-USFDACVM-2025-US-075245

USA-USFDACVM-2025-US-073483

USA-USFDACVM-2025-US-072787

USA-USFDACVM-2025-US-074897

USA-USFDACVM-2025-US-074521

USA-USFDACVM-2025-US-072505

USA-USFDACVM-2025-US-072814