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Roxee Medication Guide

Prednisone

Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.

Both Reference complete FDA data linked Rx required Liquid (Suspension) Intervet, Inc. Official label facts Owner quick guide first
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Data freshness

Reference facts
Reference refreshed
Jun 22, 2026, 10:40 a.m.

These are the reference facts Roxee uses on browse cards and quick facts.

FDA applications
FDA application data refreshed
Jun 22, 2026, 10:40 a.m.

Sponsor, product, and application records imported from Animal Drugs @ FDA.

Safety reports
Safety data refreshed
Jun 22, 2026, 10:42 a.m.

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Reference facts: Source Roxee | Refreshed Jun 22, 2026, 10:40 AM UTC
    The reference fact projection used for browse cards and quick facts.
  • Animal Drugs @ FDA: Source FDA | Refreshed Jun 22, 2026, 10:40 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • openFDA reaction terms: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
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Prednisone

Prednisone

Drug type: Generic ingredient • Generic profile • No FDA branded products linked

Both Liquid (Suspension) Rx required 100% reference complete

Species: Both

Manufacturer: Intervet, Inc.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Prednisone

Corticosteroid used for inflammatory and immune-mediated conditions. Species commonly shown: Both, Dog, Restricted During Pregnancy, Horse, Restricted During Pregnancy.

Generic name
Prednisone
Brand names
Meticorten®
Manufacturer
Intervet, Inc.
Species
Both, Dog, Horse, Cat
Dosage forms
Liquid (Suspension)
Prescription
Prescription required
Completeness
100%
Validation
Complete
Brand names
Meticorten®
Dosage forms
Liquid (Suspension)

Indications / Uses

Corticosteroid used for inflammatory and immune-mediated conditions.

Administration / How To Give

Oral

Storage

Store at room temperature.

Warnings / Contraindications

Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history.

  • Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history.

Side Effects

Increased thirst/urination, increased appetite, panting, GI upset. Long-term use: immune suppression and other risks.

FAQ

Both, Dog, Restricted During Pregnancy, Horse, Restricted During Pregnancy, Horse, Not For Meat Production, Cat, Restricted During Pregnancy

Yes. Roxee shows this as prescription-only.

Liquid (Suspension)

Store at room temperature.

Related Medications

Cyclosporine Same category: Allergies / Itching Diphenhydramine Same category: Allergies / Itching Lokivetmab Same category: Allergies / Itching Oclacitinib Same category: Allergies / Itching Oclacitinib Maleate Same category: Allergies / Itching Meloxicam Same category: Allergies / Itching

Related Conditions

Dystocia Metritis

Source Transparency

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Used for:

It is used for conditions requiring an anti-inflammatory agent.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • Avoid combining with NSAIDs
  • Use caution with diabetes, infections, GI ulcer history
  • Loss of appetite (1 reports)
  • Cough, productive (1 reports)
  • Corneal oedema (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?

Next actions

Talk to a Vet / Find a Vet Near You Save to pet meds Share page Review report evidence
Research brief

Medication Research Insights

A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.

Source Backed Signals

What to know

Evidence-backed context Limited

Roxee has limited cited overview evidence for Prednisone; use the official documents and your veterinarian's instructions for product-specific decisions.

Source: openFDA case USA-USFDACVM-2025-US-052203
Safety signal coverage Reported signals

32 tracked reaction signals; 32 reported cases; 23 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.

Source: openFDA case USA-USFDACVM-2025-US-052203
Interpretation guardrail Not causation

Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.

Evidence tension

Stronger signal Label / review

Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.

Source: openFDA case USA-USFDACVM-2025-US-052203
Weaker signal Reported data

Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.

Reaction signal map

Most reported reactions Top terms

Loss of appetite (1 reports), Cough, productive (1 reports), Corneal oedema (1 reports), Conjunctivitis (1 reports), Conjunctival oedema (1 reports)

Body systems represented Signal grouping

Digestive (1), Skin & allergy (2), Neurologic (1), Behavior (1)

Explore supporting adverse reports

Species and breed lens

Species represented in reports Species lens

Dog (20 reports), Cat (12 reports)

Breed metadata in reports Metadata only

['Corgi - Welsh Cardigan', 'Chihuahua'] (1), Domestic Shorthair (1), Terrier - Boston (1), Shepherd Dog - German (1). These are report metadata, not proof that a breed is at higher risk.

What your vet may verify

Fit for this patient Vet check

Verify whether Prednisone fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.

Evidence limitations Evidence review

Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.

What to watch next

Watch list Owner-safe

Avoid combining with NSAIDs, Use caution with diabetes, infections, GI ulcer history, Loss of appetite, Cough, productive, Corneal oedema

Call sooner if Escalation

Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.

Bottom line: Use this Prednisone brief as a structured watch list and source map, not as a reason to start, stop, or change treatment without your veterinarian.
Vet source depth
  1. openFDA case USA-USFDACVM-2025-US-052203 · adverse_reaction · adverse reactions
  2. Contraindication source · fda_animal_drugs · warnings contraindications
  3. FDA application profile · official_label · quick facts
  4. Medication usage source · fda_animal_drugs · quick facts
  5. SPL · document · documents

Evidence

Review status / Updated / Sources

Review status: Clinical reviewer not listed

Updated: February 12, 2026, 7:40 PM UTC

Sources:
Safety & side effects

Side effects to monitor:

  • Avoid combining with NSAIDs
  • Use caution with diabetes, infections, GI ulcer history
  • Loss of appetite
  • Cough, productive
  • Corneal oedema

Most reported reactions:

  • Loss of appetite (1 reports)
  • Cough, productive (1 reports)
  • Corneal oedema (1 reports)
Explore reported case details

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Vet Fast Scan

Source-backed clinical checkpoints for quick review.

FDA-labeled species
Cat, Dog, Horse
Indication / use
It is used for conditions requiring an anti-inflammatory agent.
Form / route / dose
Form: Liquid (Suspension)
Route: Intramuscular
Confirm product label and patient-specific plan.
Warnings
  • High: Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history.
Adverse-event caveat
openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.
Source docs

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Intervet, Inc.
Form: Liquid (Suspension)
Identifiers:
NADA: 9963
Source metadata:

Warnings / Contraindications

Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history.

  • High: Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Reported case explorer

Filter stored openFDA reports by pet and report attributes. Counts describe reports in this data set, not risk.

Clear filters
openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.
Stored reports
36
Matching reports
4
Active filters
2
Selected filters
Reaction: Death Clear Body system: Neurologic Clear
Reset
Drill into common report signals
Lethargy (see also Central nervous system depression in Neurological) (10) Not eating (8) Lack of efficacy - NOS (7) Death (5) Other (32) Neurologic (15) Digestive (11) Effectiveness (8)
Showing up to 50 matching reports.

USA-USFDACVM-2025-US-075245

Received 2025-12-16 · MSK · MSK

Serious
Species
Dog
Breed
Retriever - Golden
Size / weight
10-24 lb (6.622 Kilogram)
Age
Under 1 year (2 Month)
Sex
Male Intact
Region
USA
Reactions
WeaknessNot eatingLying downInappropriate urinationDifficulty standingWalking slowlyCollapse NOS (see also Cardio-vascular and Neurological disorders)Pain NOSSneezingCough, productiveInvoluntary urinationUnable to walkLeucocytosis NOSAnaemia NOSDecreased blood urea nitrogen (BUN) or creatinineAbdominal painGastric ulcerSeizure NOSDeathLack of efficacy - NOS
Body systems
OtherNeurologicEffectiveness
Outcomes
Died

USA-USFDACVM-2025-US-074897

Received 2025-12-12 · MSK · MSK

Serious
Species
Dog
Breed
['Chihuahua', 'Dog (unknown)']
Size / weight
Under 10 lb (2.26 Kilogram)
Age
Under 1 year (2 Week)
Sex
Female Intact
Region
USA
Reactions
IcterusDeathOther abnormal test result NOSElevated liver enzymes NOSSwollen jointLocalised hair lossSkin lesion NOSConjunctival oedemaCorneal oedemaSkin scabSwollen limbLethargy (see also Central nervous system depression in Neurological)AnorexiaEar infection NOSLocal swelling (not application site)
Body systems
OtherSkin & allergyNeurologicDigestive
Outcomes
Died

USA-USFDACVM-2025-US-074320

Received 2025-11-24 · MSK · MSK

Serious
Species
Dog
Breed
['Terrier (unspecified)', 'Dog (unknown)']
Size / weight
25-49 lb (18.14 Kilogram)
Age
8+ years (9 Year)
Sex
Male Neutered
Region
USA
Reactions
Behavioural disorder NOSEpidermal collaretteHepatic toxicosisDermal thickeningPyodermaJoint swellingLocal swelling (not application site)Skin ulcerLethargy (see also Central nervous system depression in Neurological)ItchingHair loss NOSDeathInappetence
Body systems
BehaviorOtherSkin & allergyNeurologic
Outcomes
Died

USA-USFDACVM-2025-US-068424

Received 2025-11-17 · MSK · MSK

Serious
Species
Dog
Breed
['Terrier (unspecified)', 'Dog (unknown)']
Size / weight
25-49 lb (18.14 Kilogram)
Age
8+ years (9 Year)
Sex
Male Neutered
Region
USA
Reactions
Behavioural disorder NOSEpidermal collaretteHepatic toxicosisDermal thickeningPyodermaJoint swellingLocal swelling (not application site)Skin ulcerLethargy (see also Central nervous system depression in Neurological)ItchingHair loss NOSDeathInappetence
Body systems
BehaviorOtherSkin & allergyNeurologic
Outcomes
Died

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
23
Species represented
2
Grouped by Body System
Digestive (1) · Loss of appetite Skin & allergy (2) · Hair loss, Application site hair loss Neurologic (1) · Unsteady walking (ataxia) Behavior (1) · Behavioral disorder (unspecified) Other (27) · Cough, productive, Corneal oedema, Conjunctivitis
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Digestive 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Dog 1
Other 1 Cat 1
Other 1 Dog 1

Species coverage: Dog (20) Cat (12)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Neurologic Cat Non-serious - 1
Digestive Dog Serious - 1
Skin & allergy Dog Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Behavior Cat Non-serious - 1
Other Cat Non-serious - 1
Other Dog Non-serious - 1
Other Cat Non-serious - 1
Skin & allergy Cat Non-serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Non-serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Source metadata:

Storage & Handling

Store at room temperature.

Source Documents

The most useful source links appear first; full previews and metadata stay in the veterinary/professional layer.

Use original documents to confirm product-specific warnings, ingredients, and handling details with your veterinarian.

Meticorten® SPL · SPL

Full source previews and metadata remain in the veterinary/professional layer.

Owner handouts

0
No owner handouts linked yet.

Official label / PI

0
No official label or package insert links yet.

SPL

1

FOI

0
No FOI links yet.

Meticorten®

SPL · SPL

Open original
FDA Structured Product Label

Meticorten®

Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.

Sponsor
Intervet, Inc.
NADA
9963
Status
RX
Form
Liquid (Suspension)
Route
Intramuscular
Species
Dog • Horse • Cat
Composition / specifications
Each milliliter of sterile aqueous suspension contains 10 to 40 milligrams of prednisone.

Horses

Indication
It is used for conditions requiring an anti-inflammatory agent.
Dosage
100 to 400 milligrams intramuscularly, repeating if necessary. If no response is observed after 3 to 4 days of therapy, reevaluate diagnosis.
Limitations
Do not use in viral infections. Except in emergency therapy, do not use in animals with tuberculosis, chronic nephritis, or Cushings's disease. With infections, use appropriate antibacterial therapy with and for at least 3 days after discontinuance of use and disappearance of all signs of infection. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta and metritis. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Dogs

Indication
It is used for conditions requiring an anti-inflammatory agent.
Dosage
0.25 to 1.0 milligram per pound of body weight for 3 to 5 days or until a response is noted. Treatment may be continued with an orally administered dose.
Limitations
Do not use in viral infections. Except in emergency therapy, do not use in animals with tuberculosis, chronic nephritis, or Cushings's disease. With infections, use appropriate antibacterial therapy with and for at least 3 days after discontinuance of use and disappearance of all signs of infection. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta and metritis. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

Cats

Indication
It is used for conditions requiring an anti-inflammatory agent.
Dosage
0.25 to 1.0 milligram per pound of body weight for 3 to 5 days or until a response is noted. Treatment may be continued with an orally administered dose.
Limitations
Do not use in viral infections. Except in emergency therapy, do not use in animals with tuberculosis, chronic nephritis, or Cushings's disease. With infections, use appropriate antibacterial therapy with and for at least 3 days after discontinuance of use and disappearance of all signs of infection. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta and metritis. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Source metadata:
Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Reference facts: Source Roxee | Refreshed Jun 22, 2026, 10:40 AM UTC
    The reference fact projection used for browse cards and quick facts.
  • Animal Drugs @ FDA: Source FDA | Refreshed Jun 22, 2026, 10:40 AM UTC
    Applications/products are imported from FDA export data.
  • Animal Drugs @ FDA previews: Source FDA | Refreshed Feb 9, 2026, 3:05 AM UTC
    Label highlights/doc links are fetched from FDA preview endpoints.
  • openFDA reaction terms: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both • FDA-labeled species: Cat, Dog, Horse
Rx/OTC: RX
Form/route: Liquid (Suspension) • Intramuscular
Applications: NADA 9963
Documents: • SPL: 1 • Label highlights • Official documents
Safety (openFDA)
Top reactions: Dog 165 • Cat 54 • View
Case summaries: 36 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Explore
Related conditions: Dystocia Metritis
Linked using: Fda_Label (0.95), Fda_Label (0.95)
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history. (Contraindication, High)
Top reaction signals
Loss of appetite (1) Cough, productive (1) Corneal oedema (1) Conjunctivitis (1) Conjunctival oedema (1) Collapse NOS (1) Cold feeling to the touch (1) Bumps on skin (1)

Identifiers & Packages

Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.

Identifiers
NADA: 9963

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 8 Clinical 4 Manufacturer 0 Marketing 0
Current Field Facts
  • side_effects: Increased thirst/urination, increased appetite, panting, GI upset. Long-term use: immune suppression and other risks. (Clinical, 2026-04-11)
  • storage_handling: Store at room temperature. (Clinical, 2026-04-12)
  • storage_handling: Store at room temperature. (Clinical, 2026-04-11)
  • storage_handling: Store at room temperature. (Clinical, 2026-02-12)
  • contraindications: Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history. (Official, 2026-04-12)
  • contraindications: Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history. (Official, 2026-04-11)
  • contraindications: Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history. (Official, 2026-02-12)
  • side_effects: Increased thirst/urination, increased appetite, panting, GI upset. Long-term use: immune suppression and other risks. (Official, 2026-04-12)
  • side_effects: Increased thirst/urination, increased appetite, panting, GI upset. Long-term use: immune suppression and other risks. (Official, 2026-02-12)
  • usage: Corticosteroid used for inflammatory and immune-mediated conditions. (Official, 2026-04-12)
  • usage: Corticosteroid used for inflammatory and immune-mediated conditions. (Official, 2026-04-11)
  • usage: Corticosteroid used for inflammatory and immune-mediated conditions. (Official, 2026-02-12)
Recent Revisions
  • side_effects updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields

FDA Products & Applications (Animal Drugs @ FDA)

Official sponsor/proprietary-name/application-status records linked by active ingredient.

Product Sponsor Application Status Published
Meticorten®
RX
Prednisone
Liquid (Suspension) • Intramuscular
Label highlights
Official documents
Intervet, Inc. NADA 9963 Approved Jun 1, 2016

Data source: FDA Animal Drugs @ FDA (public search export).

What It's For (FDA Label Highlights)

Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.

Species: Dog • Horse • Cat
Composition / specifications
Each milliliter of sterile aqueous suspension contains 10 to 40 milligrams of prednisone.
Horses
Indication
It is used for conditions requiring an anti-inflammatory agent.
Dosage
100 to 400 milligrams intramuscularly, repeating if necessary. If no response is observed after 3 to 4 days of therapy, reevaluate diagnosis.
Limitations
Do not use in viral infections. Except in emergency therapy, do not use in animals with tuberculosis, chronic nephritis, or Cushings's disease. With infections, use appropriate antibacterial therapy with and for at least 3 days after discontinuance of use and disappearance of all signs of infection. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta and metritis. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Dogs
Indication
It is used for conditions requiring an anti-inflammatory agent.
Dosage
0.25 to 1.0 milligram per pound of body weight for 3 to 5 days or until a response is noted. Treatment may be continued with an orally administered dose.
Limitations
Do not use in viral infections. Except in emergency therapy, do not use in animals with tuberculosis, chronic nephritis, or Cushings's disease. With infections, use appropriate antibacterial therapy with and for at least 3 days after discontinuance of use and disappearance of all signs of infection. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta and metritis. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Cats
Indication
It is used for conditions requiring an anti-inflammatory agent.
Dosage
0.25 to 1.0 milligram per pound of body weight for 3 to 5 days or until a response is noted. Treatment may be continued with an orally administered dose.
Limitations
Do not use in viral infections. Except in emergency therapy, do not use in animals with tuberculosis, chronic nephritis, or Cushings's disease. With infections, use appropriate antibacterial therapy with and for at least 3 days after discontinuance of use and disappearance of all signs of infection. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta and metritis. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

FDA page: Open in Animal Drugs @ FDA

Usage

Corticosteroid used for inflammatory and immune-mediated conditions.

Source: FDA Animal Drugs @ FDA • Reference

Contraindications

Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history.

Side Effects

Increased thirst/urination, increased appetite, panting, GI upset. Long-term use: immune suppression and other risks.

Source: FDA openFDA • Reference

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Loss of appetite (1) • Dog

Showing top 5 for Digestive.

Skin & allergy
Hair loss (1) • Dog Application site hair loss (1) • Cat

Showing top 5 for Skin & allergy.

Neurologic
Unsteady walking (1) • Cat

Showing top 5 for Neurologic.

Behavior
Behavioral disorder (1) • Cat

Showing top 5 for Behavior.

Other
Cough, productive (1) • Dog Corneal oedema (1) • Dog Conjunctivitis (1) • Dog Conjunctival oedema (1) • Dog Collapse NOS (1) • Dog
Show more (22)
Cold feeling to the touch (1) • Cat Bumps on skin (1) • Dog Breathing difficulty (1) • Cat Bradycardia (1) • Cat Blood in urine (1) • Dog Blepharitis (1) • Dog Balance impaired (1) • Cat Atopic allergy NOS (1) • Dog Application site scab (1) • Cat Application site dry skin (1) • Dog Anaphylaxis (1) • Dog Anaemia NOS (1) • Dog Allergic skin reaction (1) • Dog Agonal breathing (1) • Cat Abnormal ultrasound finding (1) • Dog Abnormal radiograph finding (1) • Dog Abnormal pupil light reflex (1) • Cat Abnormal menace reflex test (1) • Cat Abnormal histology NOS (1) • Dog Abnormal cytology (1) • Dog Abdominal pain (1) • Dog Abdominal oedema (1) • Cat

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, ['Corgi - Welsh Cardigan', 'Chihuahua'], Male, 13 year, 4.5 kilogram • Drug: MSK, Tablet, Oral • Reactions: Loss of hearing, Lack of efficacy - NOS • Outcome: Recovered with Sequela

  • Report ID: USA-USFDACVM-2025-US-075439
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Male
  • Age: 13.00 Year
  • Weight: 4.500 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Form: Tablet
Reactions Reported:
Loss of hearing Lack of efficacy - NOS
Outcomes: Recovered with Sequela

Cat, Domestic Shorthair, Male • Drug: MSK, Unassigned, Unknown, Dose: 5 Milligram per animal • Reactions: Not eating, Balance impaired, Application site hair loss, Application site scab • Outcome: Recovered/Normal

  • Report ID: USA-USFDACVM-2025-US-075299
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
  • Dose: 5 Milligram per animal
Reactions Reported:
Not eating Balance impaired Application site hair loss Application site scab
Outcomes: Recovered/Normal

Dog, Terrier - Boston, Female, 2 year, 8.16 kilogram • Drug: MSK, Unknown • Reactions: Rash, Hair loss • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-075064
  • Serious AE: No
  • Treated For AE: No
  • Sex: Female
  • Age: 2.00 Year
  • Weight: 8.160 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Rash Hair loss
Outcomes: Ongoing

Dog, Shepherd Dog - German, Female, 10.9 year, 44.45 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Lack of efficacy - NOS, Seizure NOS, Other abnormal test result NOS, Unsteady walking (ataxia), Musculoskeletal disorder NOS… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-075291
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 10.90 Year
  • Weight: 44.450 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Lack of efficacy - NOS Seizure NOS Other abnormal test result NOS Unsteady walking (ataxia) Musculoskeletal disorder NOS Elevated serum alkaline phosphatase
Outcomes: Ongoing

Dog, Bloodhound, Female, 5 year, 41.28 kilogram • Drug: MSK, Oral, Dose: 40 Milligram per animal • Reactions: Tiredness (lethargy), Stiffness NOS, Walking difficulty, Generalised weakness, Neutropenia… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-074895
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 5.00 Year
  • Weight: 41.280 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
  • Dose: 40 Milligram per animal
Reactions Reported:
Tiredness (lethargy) Stiffness NOS Walking difficulty Generalised weakness Neutropenia Low platelet count Pain NOS Decreased appetite Vomiting Elevated liver enzymes NOS Fluid in abdomen NOS Liver disorder NOS Other immune system disorder NOS Fever Leucopenia NOS Distension of abdomen Hypoglycaemia Anaemia NOS Indigestion
Outcomes: Ongoing

Dog, Spaniel - King Charles Cavalier, Male, 6.5 year • Drug: MSK, Unknown • Reactions: Inflammatory bowel disorder, Atopic allergy NOS, Allergic skin reaction, Blepharitis • Outcome: Outcome Unknown

  • Report ID: USA-USFDACVM-2025-US-074702
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 6.50 Year
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Inflammatory bowel disorder Atopic allergy NOS Allergic skin reaction Blepharitis
Outcomes: Outcome Unknown

Dog, ['Siberian Husky', 'Dog (unknown)'], Male, 2 year, 22 kilogram • Drug: MSK, Unknown, Dose: 7.50 Milligram per animal, Frequency: 24 per hour • Reactions: Diarrhea • Outcome: Recovered/Normal

  • Report ID: CAN-USFDACVM-2025-CA-000113
  • Serious AE: No
  • Treated For AE: No
  • Sex: Male
  • Age: 2.00 Year
  • Weight: 22.000 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Dose: 7.50 Milligram per animal
  • Frequency: 24 per hour
Reactions Reported:
Diarrhea
Outcomes: Recovered/Normal

Dog, ['Crossbred Canine/dog', 'Chihuahua'], Female, 10 year, 6.36 kilogram • Drug: MSK, Unassigned, Frequency: 24 per hour • Reactions: Dehydration, Fever, Decreased appetite • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-075314
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 10.00 Year
  • Weight: 6.360 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Form: Unassigned
  • Frequency: 24 per hour
Reactions Reported:
Dehydration Fever Decreased appetite
Outcomes: Ongoing

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

Store at room temperature.

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