USA-USFDACVM-2025-US-075108
Received 2025-12-17 · MSK · MSK
- Species
- Cat
- Breed
- Domestic Shorthair
- Size / weight
- 10-24 lb (5.443 Kilogram)
- Age
- 8+ years (12 Year)
- Sex
- Male Neutered
- Region
- USA
- Reactions
- Death
- Body systems
- Other
- Outcomes
- Died
Roxee Medication Guide
Protamine Zinc Recombinant Human Insulin
Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.
Both
Source review pending
Biologic/vaccine record
Owner quick guide first
Veterinary professional?
Showing simplified owner view. Switch to Vet View for full technical detail.
Roxee is still reviewing source support for this medication, so verified profile facts are separated from FDA activity. Manufacturer details are not yet confirmed in reference facts.
Vaccine or biologic source record.
This record is tracked as vaccine, biologic, strain, recombinant, or lot-level source data. It is not labeled here as an FDA-approved animal drug; use the source documents and veterinarian guidance.
Do not start, stop, or change treatment without your veterinarian.
Data freshness
Reference facts
Source review pending
No refresh timestamp yet
Roxee is still reviewing source support for this medication profile.
FDA applications
Regulatory match pending
No refresh timestamp yet
Roxee has safety or ingredient evidence for this medication, but a regulatory product/application match is still pending.
Safety reports
Safety data refreshed
Jun 13, 2026, 11:29 a.m.
openFDA reaction terms and case summaries are supporting evidence, not proof of causality.
Source timing details
Source timing details
-
Reference facts:
Source Roxee
| Refreshed Jun 22, 2026, 10:45 AM UTC
The reference fact projection used for browse cards and quick facts.
- openFDA reaction terms: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
- openFDA case summaries: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
Image coming soon
Protamine Zinc Recombinant Human Insulin
Protamine Zinc Recombinant Human Insulin
Drug type: Biologic/vaccine record • Generic profile • Biologic/vaccine record
Both
58% reference complete
Species: Both
Approval status: Vaccine or biologic source record. This record is tracked as vaccine, biologic, strain, recombinant, or lot-level source data. It is not labeled here as an FDA-approved animal drug; use the source documents and veterinarian guidance.
Medication Snapshot
Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.
Protamine Zinc Recombinant Human Insulin
Generic name
Protamine Zinc Recombinant Human Insulin
Species
Both
Completeness
58%
Validation
Incomplete
Side Effects
Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous system depression in 'Neurological').
FAQ
Both
Source Transparency
- Verified source: https://www.roxee.ai/meds/
- Verified source: https://animaldrugsatfda.fda.gov
- Verified source: https://api.fda.gov/animalandveterinary/event.json
- Last refreshed: Jun 22, 2026, 10:45 a.m.
- Last verified: Apr 22, 2026, 10:07 a.m.
- Validation status: Incomplete
Add to My Pet's Medications
Choose a pet, confirm current or past, and optionally add reminder notes.
Sign in to save this medication to your pet profile.
Sign in to continuePet Owner Quick Guide
Start here first for the safest next-step summary before the deeper medication detail.
Roxee still has limited plain-language guidance for this medication. Use the official documents and your veterinarian's instructions for product-specific details.
Used for:
Your vet decides this. Here's what owners typically ask/watch for.
Dosing note:
Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.
What to watch for:
- Walking difficulty (1 reports)
- wobbly/unsteady walking (1 reports)
- Underdose (1 reports)
When to call the vet:
- Repeated vomiting or diarrhea.
- Severe lethargy (hard to wake, very low energy).
- Collapse or fainting.
- Trouble breathing.
- Facial swelling or hives.
- Blood in vomit or stool.
What to tell or ask your vet today:
- Is this medicine the right fit for my pet’s current symptoms?
- Which warning signs mean I should call back right away?
- How should I handle missed doses or refusal to take the medicine?
Research brief
Medication Research Insights
A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.
What to know
Evidence-backed context
Limited
Roxee has limited cited overview evidence for Protamine Zinc Recombinant Human Insulin; use the official documents and your veterinarian's instructions for product-specific decisions.
Source: openFDA case USA-USFDACVM-2025-US-075490
Safety signal coverage
Reported signals
31 tracked reaction signals; 28 reported cases; 20 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.
Source: openFDA case USA-USFDACVM-2025-US-075490
Interpretation guardrail
Not causation
Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.
Evidence tension
Stronger signal
Label / review
Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.
Source: openFDA case USA-USFDACVM-2025-US-075490
Weaker signal
Reported data
Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.
Reaction signal map
Most reported reactions
Top terms
Walking difficulty (1 reports), Unsteady walking (ataxia) (1 reports), Underdose (1 reports), Twitching (1 reports), Shivering (1 reports)
Body systems represented
Signal grouping
Digestive (4), Skin & allergy (1), Neurologic (3), Effectiveness (3)
Species and breed lens
Species represented in reports
Species lens
Cat (25 reports), Dog (6 reports)
Breed metadata in reports
Metadata only
Domestic Shorthair (3), Cat (unknown) (2), Terrier - Yorkshire (1), Terrier - West Highland White (1). These are report metadata, not proof that a breed is at higher risk.
What your vet may verify
Fit for this patient
Vet check
Verify whether Protamine Zinc Recombinant Human Insulin fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.
Evidence limitations
Evidence review
Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.
What to watch next
Watch list
Owner-safe
Walking difficulty, wobbly/unsteady walking, Underdose
Call sooner if
Escalation
Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.
Bottom line: Use this Protamine Zinc Recombinant Human Insulin brief as a structured watch list and source map, not as a reason to start, stop, or change treatment without your veterinarian.
Vet source depth
- openFDA case USA-USFDACVM-2025-US-075490 · adverse_reaction · adverse reactions
Evidence
Review status / Updated / Sources
Review status: Clinical reviewer not listed
Updated: April 22, 2026, 10:07 AM UTC
Sources:
- openFDA case USA-USFDACVM-2025-US-075490 · adverse_reaction
Safety & side effects
Side effects to monitor:
- Walking difficulty
- wobbly/unsteady walking
- Underdose
Most reported reactions:
- Walking difficulty (1 reports)
- Unsteady walking (ataxia) (1 reports)
- Underdose (1 reports)
Emergency warning signs:
- Repeated vomiting or diarrhea.
- Severe lethargy (hard to wake, very low energy).
- Collapse or fainting.
- Trouble breathing.
Vet Fast Scan
Source-backed clinical checkpoints for quick review.
FDA-labeled species
Not linked yet
Indication / use
Your vet decides this. Here's what owners typically ask/watch for.
Form / route / dose
Confirm product label and patient-specific plan.
Warnings
No structured warnings linked yet.
Adverse-event caveat
openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.
Source docs
No source documents linked yet.
Quick Facts
Official label facts first, then secondary summaries. Marketing content is separated below.
Species: Both
Manufacturer: Manufacturer not confirmed
Identifiers:
NDC Package: 0010-4499-01
NDC Package: 0010-4499-02
NDC Product: 0010
Adverse Reactions
Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.
Reported case explorer
Filter stored openFDA reports by pet and report attributes. Counts describe reports in this data set, not risk.
openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.
Stored reports
9
Matching reports
1
Active filters
1
Selected filters
Reaction: Death
Clear
Drill into common report signals
Showing up to 50 matching reports.
Tap or hover a reaction to see what it means in plain language.
Tracked signals
31
Reported cases
28
Serious reports
20
Species represented
2
Grouped by Body System
Digestive (4)
· Vomiting, Partial anorexia, Loss of appetite
Skin & allergy (1)
· Twitching
Neurologic (3)
· Unsteady walking (ataxia), Tiredness (lethargy), Seizure NOS
Effectiveness (3)
· Lack of efficacy - NOS, Lack of efficacy (bacteria) - NOS, Lack of efficacy (bacteria) - Leptospira
Other (20)
· Walking slowly, Walking difficulty, Vocalisation
Most Reported Reactions
| Reaction | Body system | Cases | Species | Serious cases |
|---|---|---|---|---|
| Other | 1 | Dog | 1 | |
| Neurologic | 1 | Cat | 1 | |
| Other | 1 | Cat | 1 | |
| Skin & allergy | 1 | Cat | 1 | |
| Other | 1 | Dog | 1 | |
| Neurologic | 1 | Cat | 1 | |
| Other | 1 | Cat | 1 | |
| Effectiveness | 1 | Dog | 1 |
Species coverage: Cat (25) Dog (6)
View detailed reaction table
| Reaction | Body system | Species | Seriousness | Frequency | Reports |
|---|---|---|---|---|---|
| Other | Cat | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Digestive | Cat | Non-serious | - | 1 | |
| Other | Cat | Non-serious | - | 1 | |
| Other | Cat | Non-serious | - | 1 | |
| Neurologic | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Skin & allergy | Cat | Serious | - | 1 | |
| Neurologic | Cat | Non-serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Neurologic | Cat | Serious | - | 1 | |
| Digestive | Cat | Non-serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Effectiveness | Dog | Non-serious | - | 1 | |
| Effectiveness | Dog | Serious | - | 1 | |
| Effectiveness | Dog | Serious | - | 1 | |
| Other | Cat | Non-serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Dog | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Digestive | Cat | Unknown | - | - | |
| Digestive | Cat | Unknown | - | - | |
| Other | Cat | Unknown | - | - |
Source metadata:
- https://api.fda.gov/animalandveterinary/event.json · adverse_reaction · openFDA case USA-USFDACVM-2025-US-075490
Veterinary reference (advanced)
Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.
At a Glance
Quick facts and links to official labeling and safety signals.
Data freshness
-
Reference facts:
Source Roxee
| Refreshed Jun 22, 2026, 10:45 AM UTC
The reference fact projection used for browse cards and quick facts.
- openFDA reaction terms: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
- openFDA case summaries: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
Official (FDA)
Identity: Generic ingredient
• No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA):
MSK
Catalog species: Both
Diagnosis Codes
Diagnosis-code mappings are not available for this medication yet.
Counseling and Monitoring Highlights
Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.
Top reaction signals
Walking difficulty (1)
Unsteady walking (ataxia) (1)
Underdose (1)
Twitching (1)
Shivering (1)
Seizure NOS (1)
Low serum alkaline phosphatase (1)
Lack of efficacy (bacteria) - NOS (1)
Identifiers & Packages
Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.
Identifiers
NDC Package: 0010-4499-01
NDC Package: 0010-4499-02
NDC Product: 0010
| Package NDC | Product NDC | Form / Route | Status |
|---|---|---|---|
| 0010-4499-01 | 0010 | - | |
| 0010-4499-02 | 0010 | - |
Data Sources & Change Log
Every non-trivial field is expected to include provenance and update timestamps.
Official 61
Clinical 1
Manufacturer 0
Marketing 0
Current Field Facts
- side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Clinical, 2026-04-11)
- side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-06-22)
- side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-06-22)
- side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-06-21)
- side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-06-20)
- side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-06-13)
- side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-06-12)
- side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-06-12)
- side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-06-11)
- side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-06-11)
- side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-06-10)
- side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-06-08)
- side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-06-07)
- side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-06-06)
- side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-06-05)
- side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-06-04)
- side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-06-03)
- side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-06-02)
- side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-06-01)
- side_effects: Top reported reactions (openFDA): Lack of efficacy - NOS, INEFFECTIVE, GLYCEMIC CONTROL, Hypoglycaemia, Vomiting, Death, Lethargy (see also Central nervous sys… (Official, 2026-06-01)
Recent Revisions
- side_effects updated 2026-06-22 10:45 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-22 10:04 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-21 05:18 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-20 20:58 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-13 11:33 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-12 10:42 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-12 10:04 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-11 19:22 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-11 18:40 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-10 10:05 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-08 10:05 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-07 10:05 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-06 10:05 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-05 10:05 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-04 10:05 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-03 10:05 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-02 10:05 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-01 10:40 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-06-01 10:05 by etl_backfill • Backfilled from existing medication fields
- side_effects updated 2026-05-31 10:05 by etl_backfill • Backfilled from existing medication fields
Top Reported Reactions (openFDA)
De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).
Digestive
Vomiting (1)
• Cat
Partial anorexia (1)
• Cat
Loss of appetite
• Cat
Diarrhea
• Cat
Showing top 5 for Digestive.
Skin & allergy
Twitching (1)
• Cat
Showing top 5 for Skin & allergy.
Neurologic
Unsteady walking (1)
• Cat
Tiredness (1)
• Cat
Seizure NOS (1)
• Cat
Showing top 5 for Neurologic.
Effectiveness
Lack of efficacy - NOS (1)
• Dog
Lack of efficacy (bacteria) - NOS (1)
• Dog
Lack of efficacy (bacteria) - Leptospira (1)
• Dog
Showing top 5 for Effectiveness.
Other
Walking slowly (1)
• Cat
Walking difficulty (1)
• Dog
Vocalisation (1)
• Cat
Urinary tract disorder NOS (1)
• Cat
Underdose (1)
• Cat
Show more (15)
Shivering (1)
• Dog
Low serum alkaline phosphatase (1)
• Cat
INEFFECTIVE, GLYCEMIC CONTROL (1)
• Cat
Hypophosphataemia (1)
• Cat
Hyponatremia (1)
• Cat
Hypokalaemia (1)
• Cat
Hypoglycaemia (1)
• Cat
Hypochloraemia (1)
• Cat
Haemangiosarcoma (1)
• Cat
Granuloma (1)
• Dog
Elevated total bilirubin (1)
• Cat
Elevated alanine aminotransferase (1)
• Cat
Death by euthanasia (1)
• Cat
Death (1)
• Cat
Abdominal pain
• Cat
Showing top 5 for Other.
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Adverse Event Case Summaries (openFDA)
These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.
Cat, Cat (unknown), Male, 4.536 kilogram • Drug: MSK, Suspension, Unknown, Dose: 3 [iU] per animal, Frequency: 12 per hour • Reactions: INEFFECTIVE, GLYCEMIC CONTROL • Outcome: Outcome Unknown
- Report ID: USA-USFDACVM-2025-US-075105
- Serious AE: No
- Treated For AE: No
- Sex: Male
- Weight: 4.536 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
- Form: Suspension
- Dose: 3 [iU] per animal
- Frequency: 12 per hour
Reactions Reported:
INEFFECTIVE, GLYCEMIC CONTROL
Outcomes: Outcome Unknown
Cat, Cat (unknown), Male, 9 year, 6.804 kilogram • Drug: MSK, Suspension, Unknown, Frequency: 12 per hour • Reactions: Lack of efficacy - NOS • Outcome: Outcome Unknown
- Report ID: USA-USFDACVM-2025-US-075084
- Serious AE: No
- Treated For AE: No
- Sex: Male
- Age: 9.00 Year
- Weight: 6.804 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Unknown
- Form: Suspension
- Frequency: 12 per hour
Reactions Reported:
Lack of efficacy - NOS
Outcomes: Outcome Unknown
Cat, Domestic Shorthair, Female, 15 year, 6.804 kilogram • Drug: MSK, Suspension, Subcutaneous, Dose: 4 [iU] per animal, Frequency: 2 per day • Reactions: Unsteady walking (ataxia), Twitching, Seizure NOS, Hypoglycaemia, Hypokalaemia • Outcome: Ongoing
- Report ID: USA-USFDACVM-2025-US-075490
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Female
- Age: 15.00 Year
- Weight: 6.804 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Subcutaneous
- Form: Suspension
- Dose: 4 [iU] per animal
- Frequency: 2 per day
Reactions Reported:
Unsteady walking (ataxia)
Twitching
Seizure NOS
Hypoglycaemia
Hypokalaemia
Outcomes: Ongoing
Cat, Domestic Shorthair, Male, 12 year, 5.443 kilogram • Drug: MSK, Suspension, Subcutaneous, Dose: 0.60 [iU] per kilogram, Frequency: 12 per hour • Reactions: Death • Outcome: Died
- Report ID: USA-USFDACVM-2025-US-075108
- Serious AE: Yes
- Treated For AE: No
- Sex: Male
- Age: 12.00 Year
- Weight: 5.443 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Subcutaneous
- Form: Suspension
- Dose: 0.60 [iU] per kilogram
- Frequency: 12 per hour
Reactions Reported:
Death
Outcomes: Died
Cat, Domestic Shorthair, Male, 11 year, 5.942 kilogram • Drug: MSK, Suspension, Subcutaneous, Frequency: 12 per hour • Reactions: Walking slowly, Lack of efficacy - NOS • Outcome: Outcome Unknown
- Report ID: USA-USFDACVM-2025-US-074752
- Serious AE: No
- Treated For AE: No
- Sex: Male
- Age: 11.00 Year
- Weight: 5.942 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Subcutaneous
- Form: Suspension
- Frequency: 12 per hour
Reactions Reported:
Walking slowly
Lack of efficacy - NOS
Outcomes: Outcome Unknown
Dog, Terrier - Yorkshire, Male, 9 year, 3.992 kilogram • Drug: MSK, Suspension, Subcutaneous, Dose: 0.60 [iU] per kilogram, Frequency: 1 per day • Reactions: Lack of efficacy - NOS • Outcome: Outcome Unknown
- Report ID: USA-USFDACVM-2025-US-074642
- Serious AE: No
- Treated For AE: No
- Sex: Male
- Age: 9.00 Year
- Weight: 3.992 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Subcutaneous
- Form: Suspension
- Dose: 0.60 [iU] per kilogram
- Frequency: 1 per day
Reactions Reported:
Lack of efficacy - NOS
Outcomes: Outcome Unknown
Dog, Terrier - West Highland White, Female, 11 year, 6.94 kilogram • Drug: MSK, Suspension, Subcutaneous, Dose: 1.28 [iU] per kilogram, Frequency: 1 per day • Reactions: Walking difficulty, Shivering, Tiredness (lethargy), Hypoglycaemia, Lack of efficacy - NOS • Outcome: Outcome Unknown
- Report ID: USA-USFDACVM-2025-US-074658
- Serious AE: Yes
- Treated For AE: Yes
- Sex: Female
- Age: 11.00 Year
- Weight: 6.940 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Subcutaneous
- Form: Suspension
- Dose: 1.28 [iU] per kilogram
- Frequency: 1 per day
Reactions Reported:
Walking difficulty
Shivering
Tiredness (lethargy)
Hypoglycaemia
Lack of efficacy - NOS
Outcomes: Outcome Unknown
Dog, Shepherd Dog - Australian, Male, 11 year, 12.791 kilogram • Drug: MSK, Suspension, Subcutaneous, Dose: 0.48 [iU] per kilogram, Frequency: 24 per hour • Reactions: Lack of efficacy - NOS • Outcome: Outcome Unknown
- Report ID: USA-USFDACVM-2025-US-071993
- Serious AE: No
- Treated For AE: No
- Sex: Male
- Age: 11.00 Year
- Weight: 12.791 Kilogram
- Case-reported brand: MSK
- Case-reported manufacturer: MSK
- Route: Subcutaneous
- Form: Suspension
- Dose: 0.48 [iU] per kilogram
- Frequency: 24 per hour
Reactions Reported:
Lack of efficacy - NOS
Outcomes: Outcome Unknown
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Overdose Information
No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.
Storage & Handling
No approved storage guidance is linked yet for this ingredient. Use manufacturer packaging and veterinary guidance for handling/storage.
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Medical Disclaimer: The medication details provided on Roxee are for informational purposes only and are not a substitute for professional veterinary advice. Always consult your veterinarian about your pet's specific needs.