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Roxee Medication Guide

Famotidine

Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.

Both Source review pending Source coverage pending Owner quick guide first
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Data freshness

Reference facts
Source review pending
No refresh timestamp yet

Roxee is still reviewing source support for this medication profile.

FDA applications
Regulatory match pending
No refresh timestamp yet

Roxee has safety or ingredient evidence for this medication, but a regulatory product/application match is still pending.

Safety reports
Safety data refreshed
Jun 13, 2026, 11:29 a.m.

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details
Source timing details
  • Reference facts: Source Roxee | Refreshed Jun 22, 2026, 10:45 AM UTC
    The reference fact projection used for browse cards and quick facts.
  • openFDA reaction terms: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
Image coming soon
Famotidine

Famotidine

Drug type: Generic ingredient • Generic profile • Source coverage pending

Both 85% reference complete

Species: Both

Approval status: Source coverage pending. Roxee has limited supporting content for this record, but no on-page official FDA animal-drug document is linked yet. Treat it as source-limited until the ETL backfill adds official coverage.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Famotidine

Acid-reducing medication used for GI upset and reflux. Species commonly shown: Both.

Generic name
Famotidine
Species
Both
Completeness
85%
Validation
Incomplete

Indications / Uses

Acid-reducing medication used for GI upset and reflux.

Administration / How To Give

Oral

Storage

Store at room temperature.

Warnings / Contraindications

Dose adjustments may be needed in kidney disease.

  • Dose adjustments may be needed in kidney disease.

Side Effects

Generally well tolerated; occasional GI upset.

FAQ

Both

Store at room temperature.

Related Medications

Maropitant Citrate Same category: GI Omeprazole Same category: GI Praziquantel Same category: GI Trilostane Same category: GI Levetiracetam Same category: Endocrine / Hormone Methimazole Same category: Endocrine / Hormone

Source Transparency

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Used for:

Acid-reducing medication used for GI upset and reflux.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

  • Dose adjustments may be needed in kidney disease
  • wobbly/unsteady walking (1 reports)
  • Loss of appetite (1 reports)
  • Dull reflexes (1 reports)

When to call the vet:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
  • Facial swelling or hives.
  • Blood in vomit or stool.

What to tell or ask your vet today:

  • Is this medicine the right fit for my pet’s current symptoms?
  • Which warning signs mean I should call back right away?
  • How should I handle missed doses or refusal to take the medicine?

Next actions

Talk to a Vet / Find a Vet Near You Save to pet meds Share page Review report evidence
Research brief

Medication Research Insights

A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.

Source Backed Signals

What to know

Evidence-backed context Limited

Roxee has limited cited overview evidence for Famotidine; use the official documents and your veterinarian's instructions for product-specific decisions.

Source: openFDA case USA-USFDACVM-2025-US-069686
Safety signal coverage Reported signals

32 tracked reaction signals; 32 reported cases; 29 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.

Source: openFDA case USA-USFDACVM-2025-US-069686
Interpretation guardrail Not causation

Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.

Evidence tension

Stronger signal Label / review

Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.

Source: openFDA case USA-USFDACVM-2025-US-069686
Weaker signal Reported data

Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.

Reaction signal map

Most reported reactions Top terms

Unsteady walking (ataxia) (1 reports), Loss of appetite (1 reports), Dull reflexes (1 reports), Dry coat (1 reports), Distension of abdomen (1 reports)

Body systems represented Signal grouping

Digestive (3), Neurologic (1), Behavior (1), Other (27)

Explore supporting adverse reports

Species and breed lens

Species represented in reports Species lens

Dog (17 reports), Cat (15 reports)

Breed metadata in reports Metadata only

Domestic Shorthair (2), Bloodhound (1), ['Terrier - Jack Russell', 'Terrier - Bull - American Pit'] (1), ['Bichon Frise', 'Chihuahua'] (1). These are report metadata, not proof that a breed is at higher risk.

What your vet may verify

Fit for this patient Vet check

Verify whether Famotidine fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.

Evidence limitations Evidence review

Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.

What to watch next

Watch list Owner-safe

Dose adjustments may be needed in kidney disease, wobbly/unsteady walking, Loss of appetite, Dull reflexes

Call sooner if Escalation

Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.

Bottom line: Use this Famotidine brief as a structured watch list and source map, not as a reason to start, stop, or change treatment without your veterinarian.
Vet source depth
  1. openFDA case USA-USFDACVM-2025-US-069686 · adverse_reaction · adverse reactions
  2. Medication contraindications · safety_warning · warnings contraindications

Evidence

Review status / Updated / Sources

Review status: Clinical reviewer not listed

Updated: April 15, 2026, 10:04 AM UTC

Sources:
Safety & side effects

Side effects to monitor:

  • Dose adjustments may be needed in kidney disease
  • wobbly/unsteady walking
  • Loss of appetite
  • Dull reflexes

Most reported reactions:

  • Unsteady walking (ataxia) (1 reports)
  • Loss of appetite (1 reports)
  • Dull reflexes (1 reports)
Explore reported case details

Emergency warning signs:

  • Repeated vomiting or diarrhea.
  • Severe lethargy (hard to wake, very low energy).
  • Collapse or fainting.
  • Trouble breathing.
Talk to a Vet / Find a Vet Near You Start Symptom Intake

Vet Fast Scan

Source-backed clinical checkpoints for quick review.

FDA-labeled species
Not linked yet
Indication / use
Acid-reducing medication used for GI upset and reflux.
Form / route / dose
Confirm product label and patient-specific plan.
Warnings
  • High: Dose adjustments may be needed in kidney disease.
Adverse-event caveat
openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.
Source docs
No source documents linked yet.

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both
Manufacturer: Manufacturer not confirmed

Warnings / Contraindications

Dose adjustments may be needed in kidney disease.

  • High: Dose adjustments may be needed in kidney disease.
Source metadata:

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Reported case explorer

Filter stored openFDA reports by pet and report attributes. Counts describe reports in this data set, not risk.

Clear filters
openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.
Stored reports
16
Matching reports
10
Active filters
1
Selected filters
Body system: Digestive Clear
Reset
Drill into common report signals
Thrombocytopenia (5) Abnormal radiograph finding (4) Anorexia (4) Eosinopenia (4) Other (16) Digestive (10) Neurologic (4) Skin & allergy (3)
Showing up to 50 matching reports.

USA-USFDACVM-2025-US-074895

Received 2025-12-19 · MSK · MSK

Serious
Species
Dog
Breed
Bloodhound
Size / weight
50-99 lb (41.28 Kilogram)
Age
4-7 years (5 Year)
Sex
Female Neutered
Region
USA
Reactions
Lethargy (see also Central nervous system depression in Neurological)Stiffness NOSWalking difficultyGeneralised weaknessNeutropeniaLow platelet countPain NOSDecreased appetiteVomitingElevated liver enzymes NOSFluid in abdomen NOSLiver disorder NOSOther immune system disorder NOSFeverLeucopenia NOSDistension of abdomenHypoglycaemiaAnaemia NOSIndigestion
Body systems
NeurologicOtherDigestive
Outcomes
Ongoing

USA-USFDACVM-2025-US-074361

Received 2025-12-18 · MSK · MSK

Serious
Species
Dog
Breed
['Terrier - Jack Russell', 'Terrier - Bull - American Pit']
Size / weight
25-49 lb (17.236 Kilogram)
Age
1-3 years (1 Year)
Sex
Female Unknown
Region
USA
Reactions
Emesis (multiple)Hives (see also Skin)Reddening of the skinSkin irritationUrine leakageHypersensitivity reaction
Body systems
DigestiveSkin & allergyOther
Outcomes
Ongoing

USA-USFDACVM-2025-US-074553

Received 2025-12-17 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
Under 10 lb (3.969 Kilogram)
Age
8+ years (12 Year)
Sex
Female Unknown
Region
USA
Reactions
Not eatingNot drinkingVomiting bileDeath by euthanasia
Body systems
OtherDigestive
Outcomes
Euthanized

USA-USFDACVM-2025-US-072755

Received 2025-12-10 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Mediumhair
Size / weight
10-24 lb (4.627 Kilogram)
Age
1-3 years (2 Year)
Sex
Female Unknown
Region
USA
Reactions
EmesisNot eatingHidingHyperglycaemiaFeverTachycardiaTachypnoeaBloody stoolWeight lossGall bladder & bile duct disorder NOSGastric distensionIntestinal thickeningDiarrhoea
Body systems
DigestiveOther
Outcomes
Ongoing

USA-USFDACVM-2025-US-072451

Received 2025-12-01 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
10-24 lb (5.69 Kilogram)
Age
4-7 years (7 Year)
Sex
Male Neutered
Region
USA
Reactions
Lethargy (see also Central nervous system depression in Neurological)AnorexiaElevated total bilirubinElevated gamma-glutamyl transferase (GGT)Elevated serum alkaline phosphatase (ALP)Elevated alanine aminotransferase (ALT)JaundiceEnlarged liverHidingNausea
Body systems
NeurologicDigestiveOther
Outcomes
Ongoing

USA-USFDACVM-2025-US-071623

Received 2025-12-01 · MSK · MSK

Serious
Species
Dog
Breed
['Retriever - Labrador', 'Dog (unknown)']
Size / weight
25-49 lb (17.69 Kilogram)
Age
8+ years (12 Year)
Sex
Male Neutered
Region
USA
Reactions
VomitingNot eatingWeight lossIcterusLeucopenia NOSDecreased red blood cell countThrombocytopeniaElevated alanine aminotransferase (ALT)Elevated serum alkaline phosphatase (ALP)Elevated total bilirubinHigh pancreatic-specific lipaseUrinary incontinenceInfectious disease NOSOverdoseGall bladder & bile duct disorder NOSLymphopeniaNeutropeniaSplenomegalyLoose stoolPancreas disorderHepatomegalyDeath by euthanasiaHypoalbuminaemiaHypoproteinaemiaFluid in abdomen NOSElevated blood urea nitrogen (BUN)Elevated bile acidsAbnormal ultrasound findingElevated cholesterol (total)Enlarged lymph node (localised)Reduced globulinsMonocytopeniaEosinopeniaLiver nodules
Body systems
DigestiveOther
Outcomes
Euthanized

USA-USFDACVM-2025-US-074528

Received 2025-11-25 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Mediumhair
Size / weight
Under 10 lb (4.13 Kilogram)
Age
1-3 years (2 Year)
Sex
Female Neutered
Region
USA
Reactions
AnorexiaReluctant to moveVocalisationLoss of bowel controlNot urinatingEosinopeniaBasophiliaHypernatremiaThrombocytopeniaAbnormal radiograph findingThird eyelid protrusionOther ear disorder NOS
Body systems
DigestiveOther
Outcomes
Ongoing

USA-USFDACVM-2025-US-068768

Received 2025-11-14 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Mediumhair
Size / weight
Under 10 lb (4.13 Kilogram)
Age
1-3 years (2 Year)
Sex
Female Neutered
Region
USA
Reactions
AnorexiaReluctant to moveVocalisationLoss of bowel controlNot urinatingEosinopeniaBasophiliaHypernatremiaThrombocytopeniaAbnormal radiograph findingThird eyelid protrusionOther ear disorder NOS
Body systems
DigestiveOther
Outcomes
Ongoing

USA-USFDACVM-2025-US-067552

Received 2025-11-13 · MSK · MSK

Serious
Species
Dog
Breed
Shepherd Dog - German
Size / weight
50-99 lb (40.37 Kilogram)
Age
8+ years (9 Year)
Sex
Male Neutered
Region
USA
Reactions
Injection site painNot himself/herselfVomitingWobblinessUnexplained death
Body systems
OtherDigestive
Outcomes
Died

USA-USFDACVM-2025-US-069686

Received 2025-11-12 · MSK · MSK

Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
Under 10 lb (3.9 Kilogram)
Age
8+ years (14 Year)
Sex
Female Neutered
Region
USA
Reactions
Swollen limbEpistaxisDeath by euthanasiaMalaiseHeart murmurNeutropeniaThrombocytopeniaHypoalbuminaemiaIncreased drinkingHaematuriaDecreased urine concentrationElevated protein:creatinine ratioDehydrationLymphopeniaAbdominal painIntestinal disorder NOSAbnormal radiograph findingRenal failureRenal disorder NOSInflammatory bowel disorderBronchopulmonary inflammationBruisingAnaemia NOSTachycardiaPale mucous membraneElevated alanine aminotransferase (ALT)Prolonged one stage prothrombin time (OSPT)Intentional misuseMedication error NOSPolyuriaAnorexiaAzotaemiaNecropsy performedHaemorrhage NOSFractureThyroid adenomaPancreas disorder
Body systems
OtherDigestive
Outcomes
Euthanized

Tap or hover a reaction to see what it means in plain language.

Tracked signals
32
Reported cases
32
Serious reports
29
Species represented
2
Grouped by Body System
Digestive (3) · Loss of appetite, Diarrhea, Decreased appetite Neurologic (1) · Unsteady walking (ataxia) Behavior (1) · Behavioral disorder (unspecified) Other (27) · Dull reflexes, Dry coat, Distension of abdomen
Most Reported Reactions
Reaction Body system Cases Species Serious cases
Neurologic 1 Dog 1
Digestive 1 Dog 1
Other 1 Cat 1
Other 1 Cat 1
Other 1 Dog 1
Digestive 1 Cat 1
Other 1 Cat 1
Other 1 Cat 1

Species coverage: Dog (17) Cat (15)

View detailed reaction table
Reaction Body system Species Seriousness Frequency Reports
Neurologic Dog Serious - 1
Digestive Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Digestive Cat Serious - 1
Other Dog Non-serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Digestive Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Other Cat Non-serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Behavior Dog Serious - 1
Other Cat Serious - 1
Other Dog Non-serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Dog Serious - 1
Other Cat Serious - 1
Other Cat Serious - 1
Source metadata:

Storage & Handling

Store at room temperature.

Veterinary reference (advanced)

Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.

At a Glance

Quick facts and links to official labeling and safety signals.

Data freshness
  • Reference facts: Source Roxee | Refreshed Jun 22, 2026, 10:45 AM UTC
    The reference fact projection used for browse cards and quick facts.
  • openFDA reaction terms: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
  • openFDA case summaries: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
Official (FDA)
Identity: Generic ingredient • No FDA branded products linked
No official FDA brand rows linked yet for this ingredient.
Case-reported brands (openFDA): MSK
Catalog species: Both
Safety (openFDA)
Top reactions: Dog 79 • Cat 79 • View
Case summaries: 16 (showing 8) • View
openFDA reports are unverified and do not prove causation.
Diagnosis Codes

Diagnosis-code mappings are not available for this medication yet.

Counseling and Monitoring Highlights

Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.

Owner-facing counseling points
  • Dose adjustments may be needed in kidney disease. (Contraindication, High)
Top reaction signals
Unsteady walking (ataxia) (1) Loss of appetite (1) Dull reflexes (1) Dry coat (1) Distension of abdomen (1) Diarrhea (1) Dehydration (1) Decreased urine concentration (1)

Data Sources & Change Log

Every non-trivial field is expected to include provenance and update timestamps.

Official 0 Clinical 120 Manufacturer 0 Marketing 0
Current Field Facts
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-06-22)
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-06-22)
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-06-21)
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-06-20)
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-06-13)
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-06-12)
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-06-12)
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-06-11)
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-06-11)
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-06-10)
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-06-08)
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-06-07)
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-06-06)
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-06-05)
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-06-04)
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-06-03)
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-06-02)
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-06-01)
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-06-01)
  • contraindications: Dose adjustments may be needed in kidney disease. (Clinical, 2026-05-31)
Recent Revisions
  • side_effects updated 2026-06-22 10:45 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-06-22 10:45 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-06-22 10:45 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-22 10:04 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-06-22 10:04 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-06-22 10:04 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-21 05:18 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-06-21 05:18 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-06-21 05:18 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-20 20:58 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-06-20 20:58 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-06-20 20:58 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-13 11:33 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-06-13 11:33 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-06-13 11:33 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-12 10:42 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-06-12 10:42 by etl_backfill • Backfilled from existing medication fields
  • usage updated 2026-06-12 10:42 by etl_backfill • Backfilled from existing medication fields
  • side_effects updated 2026-06-12 10:04 by etl_backfill • Backfilled from existing medication fields
  • contraindications updated 2026-06-12 10:04 by etl_backfill • Backfilled from existing medication fields

Usage

Acid-reducing medication used for GI upset and reflux.

Contraindications

Dose adjustments may be needed in kidney disease.

Side Effects

Generally well tolerated; occasional GI upset.

Source: FDA openFDA • Reference

Top Reported Reactions (openFDA)

De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).

Digestive
Loss of appetite (1) • Dog Diarrhea (1) • Cat Decreased appetite (1) • Dog

Showing top 5 for Digestive.

Neurologic
Unsteady walking (1) • Dog

Showing top 5 for Neurologic.

Behavior
Behavioral disorder (1) • Dog

Showing top 5 for Behavior.

Other
Dull reflexes (1) • Cat Dry coat (1) • Cat Distension of abdomen (1) • Dog Depressed reflexes (1) • Dog Dehydration (1) • Cat
Show more (22)
Decreased urine concentration (1) • Cat Decreased red blood cell count (1) • Dog Decreased haematocrit (1) • Cat Death by euthanasia (1) • Cat Corneal ulcer (1) • Dog Cognitive disorder NOS (1) • Dog Bruising (1) • Cat Bronchopulmonary inflammation (1) • Cat Bradycardia (1) • Cat Bloody stool (1) • Cat Blood in urine (1) • Dog Basophilia (1) • Cat Balance impaired (1) • Dog Bacterial skin infection NOS (1) • Dog Azotaemia (1) • Cat Arthritis (1) • Dog Application site dry skin (1) • Dog Anaemia NOS (1) • Dog Acid-base disorder (1) • Dog Abnormal ultrasound finding (1) • Dog Abnormal radiograph finding (1) • Cat Abdominal pain (1) • Cat

Showing top 5 for Other.

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Adverse Event Case Summaries (openFDA)

These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.

Dog, Bloodhound, Female, 5 year, 41.28 kilogram • Drug: MSK, Unknown, Dose: 20 Milligram per animal • Reactions: Tiredness (lethargy), Stiffness NOS, Walking difficulty, Generalised weakness, Neutropenia… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-074895
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 5.00 Year
  • Weight: 41.280 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Dose: 20 Milligram per animal
Reactions Reported:
Tiredness (lethargy) Stiffness NOS Walking difficulty Generalised weakness Neutropenia Low platelet count Pain NOS Decreased appetite Vomiting Elevated liver enzymes NOS Fluid in abdomen NOS Liver disorder NOS Other immune system disorder NOS Fever Leucopenia NOS Distension of abdomen Hypoglycaemia Anaemia NOS Indigestion
Outcomes: Ongoing

Dog, ['Terrier - Jack Russell', 'Terrier - Bull - American Pit'], Female, 1 year, 17.236 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Vomiting, Hives, Reddening of the skin, Skin irritation, Urine leakage… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-074361
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 1.00 Year
  • Weight: 17.236 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Vomiting Hives Reddening of the skin Skin irritation Urine leakage Hypersensitivity reaction
Outcomes: Ongoing

Cat, Domestic Shorthair, Female, 12 year, 3.969 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Not eating, Not drinking, Vomiting bile, Death by euthanasia • Outcome: Euthanized

  • Report ID: USA-USFDACVM-2025-US-074553
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 12.00 Year
  • Weight: 3.969 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Not eating Not drinking Vomiting bile Death by euthanasia
Outcomes: Euthanized

Dog, ['Bichon Frise', 'Chihuahua'], Female, 15 year, 3.493 kilogram • Drug: MSK, Unassigned, Unknown, Frequency: 1 per day • Reactions: Seizure NOS, Unsteady walking (ataxia), Urinary incontinence • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-074064
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 15.00 Year
  • Weight: 3.493 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
  • Frequency: 1 per day
Reactions Reported:
Seizure NOS Unsteady walking (ataxia) Urinary incontinence
Outcomes: Ongoing

Dog, Pinscher - Miniature, Female, 10 year, 4.037 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Tiredness (lethargy), Trembling, Limping, Head down, Walking difficulty… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-072814
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 10.00 Year
  • Weight: 4.037 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Tiredness (lethargy) Trembling Limping Head down Walking difficulty Fever Lack of efficacy - NOS Elevated globulins Blood in urine Immune-mediated polyarthropathy Elevated protein:creatinine ratio Proteinuria Intentional misuse
Outcomes: Ongoing

Cat, Domestic Mediumhair, Female, 2 year, 4.627 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Vomiting, Not eating, Hiding, Hyperglycaemia, Fever… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-072755
  • Serious AE: Yes
  • Treated For AE: Yes
  • Sex: Female
  • Age: 2.00 Year
  • Weight: 4.627 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
  • Form: Unassigned
Reactions Reported:
Vomiting Not eating Hiding Hyperglycaemia Fever Tachycardia Tachypnoea Bloody stool Weight loss Gall bladder & bile duct disorder NOS Gastric distension Intestinal thickening Diarrhea
Outcomes: Ongoing

Dog, ['Retriever - Golden', 'Dog (unknown)'], Male, 2.66 year, 27.48 kilogram • Drug: MSK, Oral • Reactions: Hives, Local erythema • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-072294
  • Serious AE: No
  • Treated For AE: Yes
  • Sex: Male
  • Age: 2.66 Year
  • Weight: 27.480 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Oral
Reactions Reported:
Hives Local erythema
Outcomes: Ongoing

Cat, Domestic Shorthair, Male, 7 year, 5.69 kilogram • Drug: MSK, Unknown • Reactions: Tiredness (lethargy), Loss of appetite, Elevated total bilirubin, Elevated gamma-glutamyl transferase, Elevated serum alkaline phosphatase… • Outcome: Ongoing

  • Report ID: USA-USFDACVM-2025-US-072451
  • Serious AE: Yes
  • Treated For AE: No
  • Sex: Male
  • Age: 7.00 Year
  • Weight: 5.690 Kilogram
  • Case-reported brand: MSK
  • Case-reported manufacturer: MSK
  • Route: Unknown
Reactions Reported:
Tiredness (lethargy) Loss of appetite Elevated total bilirubin Elevated gamma-glutamyl transferase Elevated serum alkaline phosphatase Elevated alanine aminotransferase Jaundice Enlarged liver Hiding Nausea
Outcomes: Ongoing

Data source: FDA openFDA Animal & Veterinary adverse event reports.

Overdose Information

No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.

Storage & Handling

Store at room temperature.

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