Roxee Medication Guide

Gabapentin

Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.

Both Reference partial Not FDA-approved for animals Multiple FDA labelers Official label facts Owner quick guide first

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Some reference facts for this medication are still being verified.

Not FDA-approved as an animal drug. No FDA-approved animal-drug application is linked for this record. It may represent extra-label, human-drug, bulk-compounding, export-only, or otherwise unapproved animal-use source data; use only under veterinarian direction. Do not start, stop, or change treatment without your veterinarian.

Data freshness

Reference facts

Reference refreshed

Jun 22, 2026, 10:45 a.m.

Roxee has a partial reference profile for this medication. Some primary facts still need verification.

FDA applications

FDA application data refreshed

Jun 22, 2026, 10:41 a.m.

Sponsor, product, and application records imported from Animal Drugs @ FDA.

Safety reports

Safety data refreshed

Jun 22, 2026, 10:42 a.m.

openFDA reaction terms and case summaries are supporting evidence, not proof of causality.

Source timing details

Reference facts: Source Roxee | Refreshed Jun 22, 2026, 10:45 AM UTC
The reference fact projection used for browse cards and quick facts.
Animal Drug Product Listing Directory (NDC): Source FDA | Refreshed Jun 22, 2026, 10:41 AM UTC
Package/product NDCs from FDA’s electronic listing directory (XLS).
openFDA reaction terms: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC
openFDA case summaries: Source FDA openFDA | Refreshed Jun 22, 2026, 10:45 AM UTC

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Gabapentin

Drug type: Generic ingredient • Branded profile • Not FDA-approved for animals

Both 86% reference complete

Species: Both

Approval status: Not FDA-approved as an animal drug. No FDA-approved animal-drug application is linked for this record. It may represent extra-label, human-drug, bulk-compounding, export-only, or otherwise unapproved animal-use source data; use only under veterinarian direction.

Medication Snapshot

Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.

Gabapentin

Used for neuropathic pain and as an adjunct for seizure control; also used for situational anxiety/sedation in some cases. Species commonly shown: Both.

Generic name

Gabapentin

Brand names

SolutitionKits, Gabapentin

Manufacturer

Multiple FDA labelers

Species

Both

Completeness

86%

Validation

Incomplete

Brand names

SolutitionKits Gabapentin

Indications / Uses

Used for neuropathic pain and as an adjunct for seizure control; also used for situational anxiety/sedation in some cases.

Administration / How To Give

Oral

Storage

Store at room temperature.

Warnings / Contraindications

Use caution with kidney disease; dose adjustments may be needed.

Use caution with kidney disease; dose adjustments may be needed.

Side Effects

Sedation, ataxia, mild GI upset.

FAQ

Both

Store at room temperature.

Related Medications

Related Conditions

Pain (acute, chronic)

Source Transparency

Verified source: https://www.roxee.ai/meds/
Verified source: https://animaldrugsatfda.fda.gov
Verified source: https://animaldrugsatfda.fda.gov/adafda/views/#/search
Verified source: https://api.fda.gov/animalandveterinary/event.json
Verified source: https://www.roxee.ai/conditions/
Verified source: /static/meds/images/gabapentin.jpg
Last refreshed: Jun 22, 2026, 10:45 a.m.
Last verified: Apr 15, 2026, 10:04 a.m.
Validation status: Incomplete

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Pet Owner Quick Guide

Start here first for the safest next-step summary before the deeper medication detail.

Used for:

Used for neuropathic pain and as an adjunct for seizure control; also used for situational anxiety/sedation in some cases.

Dosing note:

Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.

What to watch for:

Use caution with kidney disease
dose adjustments may be needed
wobbly/unsteady walking (1 reports)
Loss of appetite (1 reports)
Bloody diarrhoea (1 reports)

When to call the vet:

Repeated vomiting or diarrhea.
Severe lethargy (hard to wake, very low energy).
Collapse or fainting.
Trouble breathing.
Facial swelling or hives.
Blood in vomit or stool.

What to tell or ask your vet today:

Is this medicine the right fit for my pet’s current symptoms?
Which warning signs mean I should call back right away?
How should I handle missed doses or refusal to take the medicine?

Next actions

Talk to a Vet / Find a Vet Near You Save to pet meds Share page Review report evidence

Research brief

Medication Research Insights

A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.

Source Backed Signals

What to know

Evidence-backed context Limited

Roxee has limited cited overview evidence for Gabapentin; use the official documents and your veterinarian's instructions for product-specific decisions.

Source: openFDA case USA-USFDACVM-2025-US-070810

Safety signal coverage Reported signals

32 tracked reaction signals; 32 reported cases; 25 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.

Source: openFDA case USA-USFDACVM-2025-US-070810

Interpretation guardrail Not causation

Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.

Evidence tension

Stronger signal Label / review

Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.

Source: openFDA case USA-USFDACVM-2025-US-070810

Weaker signal Reported data

Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.

Reaction signal map

Most reported reactions Top terms

Unsteady walking (ataxia) (1 reports), Loss of appetite (1 reports), Bloody diarrhoea (1 reports), Blood in vomit (1 reports), Blood in urine (1 reports)

Body systems represented Signal grouping

Digestive (3), Skin & allergy (3), Neurologic (1), Behavior (3)

Explore supporting adverse reports

Species and breed lens

Species represented in reports Species lens

Dog (18 reports), Cat (14 reports)

Breed metadata in reports Metadata only

Shepherd Dog - German (2), Domestic Shorthair (2), Siamese (1), Siberian Husky (1). These are report metadata, not proof that a breed is at higher risk.

What your vet may verify

Fit for this patient Vet check

Verify whether Gabapentin fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.

Evidence limitations Evidence review

Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.

What to watch next

Watch list Owner-safe

Use caution with kidney disease, dose adjustments may be needed, wobbly/unsteady walking, Loss of appetite, Bloody diarrhoea

Call sooner if Escalation

Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.

Bottom line: Use this Gabapentin brief as a structured watch list and source map, not as a reason to start, stop, or change treatment without your veterinarian.

Vet source depth

openFDA case USA-USFDACVM-2025-US-070810 · adverse_reaction · adverse reactions
Medication contraindications · safety_warning · warnings contraindications
Structured Product Label · document · documents
Structured Product Label · document · documents
Structured Product Label · document · documents
Structured Product Label · document · documents

Evidence

Review status / Updated / Sources

Review status: Clinical reviewer not listed

Updated: April 15, 2026, 10:04 AM UTC

Sources:

Medication contraindications · safety_warning
openFDA case USA-USFDACVM-2025-US-070810 · adverse_reaction
Structured Product Label · document
Structured Product Label · document
Structured Product Label · document

Safety & side effects

Side effects to monitor:

Use caution with kidney disease
dose adjustments may be needed
wobbly/unsteady walking
Loss of appetite
Bloody diarrhoea

Most reported reactions:

Unsteady walking (ataxia) (1 reports)
Loss of appetite (1 reports)
Bloody diarrhoea (1 reports)

Explore reported case details

Emergency warning signs:

Repeated vomiting or diarrhea.
Severe lethargy (hard to wake, very low energy).
Collapse or fainting.
Trouble breathing.

Talk to a Vet / Find a Vet Near You Start Symptom Intake

Vet Fast Scan

Source-backed clinical checkpoints for quick review.

FDA-labeled species

Not linked yet

Indication / use

Used for neuropathic pain and as an adjunct for seizure control; also used for situational anxiety/sedation in some cases.

Form / route / dose

Confirm product label and patient-specific plan.

Warnings

High: Use caution with kidney disease; dose adjustments may be needed.

Adverse-event caveat

openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.

Source docs

Quick Facts

Official label facts first, then secondary summaries. Marketing content is separated below.

Species: Both

Manufacturer: Multiple FDA labelers

Identifiers:

NDC Package: 46144-600-01 NDC Package: 62157-711-01 NDC Package: 73377-176-01 NDC Package: 86032-041-01 NDC Product: 46144 NDC Product: 62157 NDC Product: 73377 NDC Product: 86032

Warnings / Contraindications

Use caution with kidney disease; dose adjustments may be needed.

High: Use caution with kidney disease; dose adjustments may be needed.

Source metadata:

https://animaldrugsatfda.fda.gov · safety_warning · Medication contraindications

Adverse Reactions

Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.

Reported case explorer

Filter stored openFDA reports by pet and report attributes. Counts describe reports in this data set, not risk.

Clear filters

openFDA adverse-event cases are reported signals. They are not verified, do not prove causation, and do not estimate a pet's individual risk.

Stored reports

Matching reports

Active filters

Selected filters

Body system: Other Clear

Species

Breed

Size / weight

Age

Sex

Seriousness

Outcome

Reaction

Body system

Region

Received after

Received before

Reset

Drill into common report signals

Lethargy (see also Central nervous system depression in Neurological) (13) Lack of efficacy - NOS (12) Seizure NOS (12) Abnormal radiograph finding (11) Other (74) Digestive (29) Neurologic (27) Effectiveness (18)

Showing up to 50 matching reports. Narrow filters to inspect the remaining reports.

USA-USFDACVM-2025-US-075421

Received 2025-12-29 · MSK · MSK

Serious

Species: Dog
Breed: Shepherd Dog - German
Size / weight: 25-49 lb (20.865 Kilogram)
Age: 8+ years (11 Year)
Sex: Female Unknown
Region: USA
Reactions: Emesis (multiple)Not eatingLethargy (see also Central nervous system depression in Neurological)Reluctant to moveSeizure NOS
Body systems: DigestiveOtherNeurologic
Outcomes: Ongoing

USA-USFDACVM-2025-US-075379

Received 2025-12-23 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (8.618 Kilogram)
Age: 4-7 years (7 Year)
Sex: Male Neutered
Region: USA
Reactions: Injection site hair lossReddening of the skinWeight lossSkin lesion NOSWoundAbnormal cytologyDiscomfort NOSSkin necrosisItchingFacial swelling (see also Skin)Facial rash (For urticaria see Immune SOC)
Body systems: Skin & allergyOther
Outcomes: Ongoing

USA-USFDACVM-2025-US-075223

Received 2025-12-23 · MSK · MSK

Serious

Species: Cat
Breed: Siamese
Size / weight: Under 10 lb (3.88 Kilogram)
Age: 8+ years (15 Year)
Sex: Male Neutered
Region: USA
Reactions: Lack of efficacy - NOSUrinary tract infectionBehavioural disorder NOSDecreased haematocritOliguria
Body systems: EffectivenessOtherBehavior
Outcomes: Outcome Unknown

USA-USFDACVM-2025-US-075044

Received 2025-12-23 · MSK · MSK

Serious

Species: Dog
Breed: Siberian Husky
Size / weight: 50-99 lb (26.58 Kilogram)
Age: 8+ years (11 Year)
Sex: Female Neutered
Region: USA
Reactions: Clonic seizureBiting -aggression (see also Skin and appendages disorders)Partial blindnessSeizure NOSFoaming at the mouthOral bleedingLethargy (see also Central nervous system depression in Neurological)WobblinessUnable to focusUrinationLateral recumbencyVocalisationBalance problemStaringElevated alanine aminotransferase (ALT)Elevated serum alkaline phosphatase (ALP)
Body systems: NeurologicBehaviorOther
Outcomes: Ongoing

USA-USFDACVM-2025-US-075455

Received 2025-12-22 · MSK · MSK

Serious

Species: Cat
Breed: Domestic Shorthair
Size / weight: 10-24 lb (4.754 Kilogram)
Age: 8+ years (11 Year)
Sex: Female Unknown
Region: USA
Reactions: Miliary dermatitisExcoriation
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2025-US-075305

Received 2025-12-22 · MSK · MSK

Non-serious

Species: Dog
Breed: Bulldog - English
Size / weight: 50-99 lb (29.94 Kilogram)
Age: 8+ years (11.2 Year)
Sex: Female Unknown
Region: USA
Reactions: Urinary incontinence
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2025-US-075291

Received 2025-12-22 · MSK · MSK

Serious

Species: Dog
Breed: Shepherd Dog - German
Size / weight: 50-99 lb (44.45 Kilogram)
Age: 8+ years (10.9 Year)
Sex: Female Unknown
Region: USA
Reactions: Lack of efficacy - NOSSeizure NOSOther abnormal test result NOSAtaxiaMusculoskeletal disorder NOSElevated serum alkaline phosphatase (ALP)
Body systems: EffectivenessNeurologicOther
Outcomes: Ongoing

USA-USFDACVM-2025-US-075189

Received 2025-12-22 · MSK · MSK

Serious

Species: Dog
Breed: ['Retriever - Golden', 'Beagle', 'Chow Chow']
Size / weight: 25-49 lb (19.504 Kilogram)
Age: 8+ years (11 Year)
Sex: Male Neutered
Region: USA
Reactions: AtaxiaVestibular disorder NOSWeight lossHead tilt - neurological disorder (see also Head tilt - ear disorder)Low visionUrinary incontinenceUnable to riseUrinary tract infectionPolydipsiaHorizontal nystagmusGeneralised weaknessDepression
Body systems: NeurologicOther
Outcomes: Ongoing

USA-USFDACVM-2025-US-074820

Received 2025-12-22 · MSK · MSK

Non-serious

Species: Dog
Breed: Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog)
Age: 4-7 years (4.8 Year)
Sex: Male Neutered
Region: USA
Reactions: LimpingSwelling NOSLimb non-weight bearingConstipationLack of efficacy (endoparasite) - heartwormPain NOSPica NOSLocalised pain NOS (see other SOCs for specific pain)
Body systems: OtherSkin & allergyEffectiveness
Outcomes: Outcome Unknown

USA-USFDACVM-2025-US-075413

Received 2025-12-19 · MSK · MSK

Serious

Species: Dog
Breed: Crossbred Canine/dog
Size / weight: 50-99 lb (30.119 Kilogram)
Age: 8+ years (12 Year)
Sex: Male Neutered
Region: USA
Reactions: Not eatingVomitingLymphadenopathyHalitosisLow platelet countElevated alanine aminotransferase (ALT)Elevated serum alkaline phosphatase (ALP)Anxiety
Body systems: OtherDigestiveBehavior
Outcomes: Ongoing

USA-USFDACVM-2025-US-074895

Received 2025-12-19 · MSK · MSK

Serious

Species: Dog
Breed: Bloodhound
Size / weight: 50-99 lb (41.28 Kilogram)
Age: 4-7 years (5 Year)
Sex: Female Neutered
Region: USA
Reactions: Lethargy (see also Central nervous system depression in Neurological)Stiffness NOSWalking difficultyGeneralised weaknessNeutropeniaLow platelet countPain NOSDecreased appetiteVomitingElevated liver enzymes NOSFluid in abdomen NOSLiver disorder NOSOther immune system disorder NOSFeverLeucopenia NOSDistension of abdomenHypoglycaemiaAnaemia NOSIndigestion
Body systems: NeurologicOtherDigestive
Outcomes: Ongoing

USA-USFDACVM-2025-US-074497

Received 2025-12-19 · MSK · MSK

Non-serious

Species: Dog
Breed: ['Terrier - Scottish', 'Dog (unknown)']
Size / weight: 10-24 lb (11.249 Kilogram)
Age: 8+ years (16 Year)
Sex: Male Neutered
Region: USA
Reactions: RestlessnessStaringConfusionDifficulty eating NOSAnxietyElevated blood urea nitrogen (BUN)Elevated serum alkaline phosphatase (ALP)
Body systems: OtherBehavior
Outcomes: Ongoing

USA-USFDACVM-2025-US-074457

Received 2025-12-19 · MSK · MSK

Serious

Species: Dog
Breed: ['Beagle', 'Dog (unknown)']
Size / weight: 25-49 lb (14.061 Kilogram)
Age: 1-3 years (3.5 Year)
Sex: Male Neutered
Region: USA
Reactions: Lethargy (see also Central nervous system depression in Neurological)AgitationSeizure NOSElevated symmetrical dimethylarginine (SDMA)FallingStiffness NOSConfusionShivering
Body systems: NeurologicOther
Outcomes: Outcome Unknown

USA-USFDACVM-2025-US-073901

Received 2025-12-19 · MSK · MSK

Serious

Species: Dog
Breed: Terrier - Bull - American Pit
Size / weight: 50-99 lb (37 Kilogram)
Age: 4-7 years (7 Year)
Sex: Male Neutered
Region: USA
Reactions: Loose stoolEmesis (multiple)Decreased appetiteDecreased drinkingMedication error NOSLack of efficacy - NOS
Body systems: OtherDigestiveEffectiveness
Outcomes: Ongoing

USA-USFDACVM-2025-US-074692

Received 2025-12-18 · MSK · MSK

Non-serious

Species: Cat
Breed: American Shorthair
Size / weight: Under 10 lb (4.5 Kilogram)
Age: 4-7 years (4.83 Year)
Sex: Female Neutered
Region: USA
Reactions: Not eatingWalking difficultyFallingUnable to standAnisocoriaThird eyelid protrusion
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2025-US-074070

Received 2025-12-18 · MSK · MSK

Serious

Species: Dog
Breed: ['Retriever - Golden', 'Poodle (unspecified)']
Size / weight: 50-99 lb (43.273 Kilogram)
Age: 8+ years (12 Year)
Sex: Female Unknown
Region: USA
Reactions: Urinary tract infectionMedication error NOSLack of efficacy - NOS
Body systems: OtherEffectiveness
Outcomes: Ongoing

USA-USFDACVM-2025-US-075336

Received 2025-12-17 · MSK · MSK

Serious

Species: Dog
Breed: Chihuahua
Size / weight: Under 10 lb (2.54 Kilogram)
Age: 8+ years (15.5 Year)
Sex: Female Unknown
Region: USA
Reactions: SyncopeInvoluntary defecationDecreased body temperatureLymphopeniaThrombocytosisElevated serum alkaline phosphatase (ALP)Medication error NOSPulmonary hypertension
Body systems: Other
Outcomes: Ongoing

USA-USFDACVM-2025-US-074412

Received 2025-12-17 · MSK · MSK

Non-serious

Species: Dog
Breed: ['Shepherd Dog - German', 'Siberian Husky']
Size / weight: 50-99 lb (35.063 Kilogram)
Age: 8+ years (14 Year)
Sex: Male Neutered
Region: USA
Reactions: Sleep disturbance NOSAnxietyPanting
Body systems: OtherBehavior
Outcomes: Ongoing