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Roxee Medication Guide
Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.
Veterinary professional?
These are the reference facts Roxee uses on browse cards and quick facts.
Sponsor, product, and application records imported from Animal Drugs @ FDA.
openFDA reaction terms and case summaries are supporting evidence, not proof of causality.
Drug type: Generic ingredient • Branded profile • FDA branded products available
Species: Cat
Manufacturer: Multiple FDA labelers
Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.
Used to manage hyperthyroidism in cats. Species commonly shown: Cat.
Used to manage hyperthyroidism in cats.
Oral
Store at room temperature.
Use caution with liver disease, blood disorders, or autoimmune conditions.
Vomiting, decreased appetite, lethargy, facial itching. Rare: low blood cell counts.
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Used for:
Methimazole Oral Solution is indicated for the treatment of hyperthyroidism in cats.
Dosing note:
Exact dosing depends on your pet's species, weight, and health status. Use your veterinarian's instructions for the exact dose and schedule.
What to watch for:
When to call the vet:
What to tell or ask your vet today:
A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.
Roxee has limited cited overview evidence for Methimazole; use the official documents and your veterinarian's instructions for product-specific decisions.
32 tracked reaction signals; 32 reported cases; 29 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.
Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.
Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.
Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.
Unsteady walking (ataxia) (1 reports), Loss of appetite (1 reports), Elevated blood urea nitrogen (1 reports), Elevated amylase (1 reports), Elevated alanine aminotransferase (1 reports)
Digestive (2), Neurologic (1), Behavior (2), Other (27)
Cat (31 reports), Dog (1 reports)
Domestic Shorthair (5), Domestic Mediumhair (2), Shepherd Dog - Australian (1). These are report metadata, not proof that a breed is at higher risk.
Verify whether Methimazole fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.
Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.
Use caution with liver disease, blood disorders, or autoimmune conditions, wobbly/unsteady walking, Loss of appetite, Elevated blood urea nitrogen
Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.
Review status / Updated / Sources
Review status: Clinical reviewer not listed
Updated: February 12, 2026, 7:40 PM UTC
Side effects to monitor:
Most reported reactions:
Emergency warning signs:
Source-backed clinical checkpoints for quick review.
Official label facts first, then secondary summaries. Marketing content is separated below.
Use caution with liver disease, blood disorders, or autoimmune conditions.
Snapshot first, detailed rows second. This section summarizes signal data and is not a diagnosis.
Filter stored openFDA reports by pet and report attributes. Counts describe reports in this data set, not risk.
Received 2026-03-25 · MSK · MSK
Received 2026-03-24 · MSK · MSK
Received 2025-12-12 · MSK · MSK
Tap or hover a reaction to see what it means in plain language.
| Reaction | Body system | Cases | Species | Serious cases |
|---|---|---|---|---|
| Neurologic | 1 | Cat | 1 | |
| Digestive | 1 | Cat | 1 | |
| Other | 1 | Cat | 1 | |
| Other | 1 | Cat | 1 | |
| Other | 1 | Cat | 1 | |
| Other | 1 | Cat | 1 | |
| Other | 1 | Cat | 1 | |
| Other | 1 | Cat | 1 |
Species coverage: Cat (31) Dog (1)
| Reaction | Body system | Species | Seriousness | Frequency | Reports |
|---|---|---|---|---|---|
| Neurologic | Cat | Serious | - | 1 | |
| Digestive | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Non-serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Non-serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Digestive | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Behavior | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Behavior | Dog | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Non-serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 | |
| Other | Cat | Serious | - | 1 |
Store at room temperature.
The most useful source links appear first; full previews and metadata stay in the veterinary/professional layer.
Use original documents to confirm product-specific warnings, ingredients, and handling details with your veterinarian.
Full source previews and metadata remain in the veterinary/professional layer.
SPL · SPL
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Methimazole Oral Solution is indicated for the treatment of hyperthyroidism in cats.
Administer a starting dose of 2.5 mg every 12 hours. Following 3 weeks of treatment, the dose should be titrated to effect based on individual serum total T4 (TT4) levels and clinical response. Dose adjustments should be made in 2.5 mg increments with a maximum dosage of 20 mg per day divided, not to exceed 10 mg as a single dose.
SPL · SPL
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
SPL · SPL
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
For the treatment of hyperthyroidism in cats.
The starting dose is 2.5 mg administered every 12 hours. Following 3 weeks of treatment, the dose should be titrated to effect based on individual serum total T4 (TT4) levels and clinical response. Dose adjustments should be made in 2.5 mg increments. The maximum total dosage is 20 mg per day divided, not to exceed 10 mg as a single administration.
SPL · SPL
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
For the treatment of hyperthyroidism in cats.
The starting dose of Methimazole Coated Tablets is 2.5 mg administered every 12 hours. Following 3 weeks of treatment, the dose should be titrated to effect based on individual serum total T4 (TT4) levels and clinical response. Dose adjustments should be made in 2.5 mg increments. The maximum total dosage is 20 mg per day divided, not to exceed 10 mg as a single administration.
SPL · Structured Product Label
SPL · Structured Product Label
SPL · Structured Product Label
SPL · Structured Product Label
SPL · Structured Product Label
SPL · Structured Product Label
SPL · Structured Product Label
SPL · Structured Product Label
FOI · FOI
FOI · FOI
FOI · FOI
FOI · FOI
Canonical medication sections are above. This legacy block remains available for deeper cross-reference without cluttering the primary workflow.
Quick facts and links to official labeling and safety signals.
Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.
Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.
| Package NDC | Product NDC | Form / Route | Status |
|---|---|---|---|
| 11695-7048-1 | 11695 | - | |
| 11695-7049-1 | 11695 | - | |
| 17033-225-10 | 17033 | - | |
| 17033-250-10 | 17033 | - | |
| 51311-044-30 | 51311 | - | |
| 51311-044-40 | 51311 | - | |
| 55529-170-02 | 55529 | - | |
| 55529-170-14 | 55529 | - | |
| 86032-064-01 | 86032 | - | |
| 86101-059-11 | 86101 | - | |
| 86101-060-11 | 86101 | - | |
| 86136-157-36 | 86136 | - | |
| 86136-158-36 | 86136 | - |
Documents are tiered by source trust: Official, Clinical, Manufacturer, Marketing.
Every non-trivial field is expected to include provenance and update timestamps.
Official sponsor/proprietary-name/application-status records linked by active ingredient.
| Product | Sponsor | Application | Status | Published |
|---|---|---|---|---|
|
Methimazole Oral Solution
RX
Methimazole
Oral Solution
• Oral
|
Felix Pharmaceuticals Pvt. Ltd. | ANADA 200-860 | Approved | Aug 3, 2026 |
|
Felimazole®
RX
Methimazole
Coated Tablets
• Oral
|
Dechra Veterinary Products LLC | NADA 141-292 | Approved | Jul 14, 2026 |
|
Felanorm®
RX
Methimazole
Oral Solution
• Oral
|
Virbac AH, Inc. | ANADA 200-771 | Approved | Jan 26, 2026 |
|
Methimazole Coated Tablets
RX
Methimazole
Coated Tablets
• Oral
|
Felix Pharmaceuticals Pvt. Ltd. | ANADA 200-814 | Approved | Jul 1, 2025 |
Data source: FDA Animal Drugs @ FDA (public search export).
Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.
Methimazole Oral Solution is indicated for the treatment of hyperthyroidism in cats.
Administer a starting dose of 2.5 mg every 12 hours. Following 3 weeks of treatment, the dose should be titrated to effect based on individual serum total T4 (TT4) levels and clinical response. Dose adjustments should be made in 2.5 mg increments with a maximum dosage of 20 mg per day divided, not to exceed 10 mg as a single dose.
FDA page: Open in Animal Drugs @ FDA
FDA page: Open in Animal Drugs @ FDA
For the treatment of hyperthyroidism in cats.
The starting dose is 2.5 mg administered every 12 hours. Following 3 weeks of treatment, the dose should be titrated to effect based on individual serum total T4 (TT4) levels and clinical response. Dose adjustments should be made in 2.5 mg increments. The maximum total dosage is 20 mg per day divided, not to exceed 10 mg as a single administration.
FDA page: Open in Animal Drugs @ FDA
For the treatment of hyperthyroidism in cats.
The starting dose of Methimazole Coated Tablets is 2.5 mg administered every 12 hours. Following 3 weeks of treatment, the dose should be titrated to effect based on individual serum total T4 (TT4) levels and clinical response. Dose adjustments should be made in 2.5 mg increments. The maximum total dosage is 20 mg per day divided, not to exceed 10 mg as a single administration.
FDA page: Open in Animal Drugs @ FDA
Used to manage hyperthyroidism in cats.
Source: FDA Animal Drugs @ FDA • Reference
Use caution with liver disease, blood disorders, or autoimmune conditions.
Vomiting, decreased appetite, lethargy, facial itching. Rare: low blood cell counts.
Source: FDA openFDA • Reference
De-duplicated reaction terms grouped by body system from FDA openFDA reports (not verified; does not prove causation).
Showing top 5 for Digestive.
Showing top 5 for Neurologic.
Showing top 5 for Behavior.
Showing top 5 for Other.
Data source: FDA openFDA Animal & Veterinary adverse event reports.
These are individual FDA adverse event reports. They are unverified and do not prove the medication caused the reaction.
Cat, Domestic Shorthair, Female, 16 year, 2.767 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Medication error NOS, Vomiting, Not eating • Outcome: Ongoing
Cat, Domestic Mediumhair, Male, 13 year, 5.897 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Skin scab • Outcome: Recovered/Normal
Cat, Domestic Shorthair, Female, 20 year, 2.631 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Agitation, Vocalisation, Unsteady walking (ataxia), Weakness • Outcome: Recovered/Normal
Cat, Domestic Shorthair, Female, 12.5 year, 2.268 kilogram • Drug: MSK, Unassigned, Unknown, Dose: 5 Milligram per animal, Frequency: 12 per hour • Reactions: Seizure NOS, Accidental exposure, Labeled drug-species interaction • Outcome: Ongoing
Cat, Domestic Mediumhair, Female, 13 year, 3.266 kilogram • Drug: MSK, Unassigned, Oral • Reactions: Constipation, Unable to stand, Hypothermia, Tachycardia, Tachypnoea… • Outcome: Ongoing
Cat, Domestic Shorthair, Female, 15 year, 3.81 kilogram • Drug: MSK, Unassigned, Unknown, Frequency: 12 per hour • Reactions: Drunken gait, Pacing, Stupor, Abnormal menace reflex test, Abnormal pupil light reflex… • Outcome: Ongoing
Dog, Shepherd Dog - Australian, Female, 9.9 year, 19.5 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Whining, Anxiety, Itching, Urine leakage, Lack of efficacy - NOS • Outcome: Outcome Unknown
Cat, Domestic Shorthair, Female, 16 year, 3.992 kilogram • Drug: MSK, Unassigned, Unknown • Reactions: Tendon rupture • Outcome: Ongoing
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Overdose may intensify side effects and can lead to overt hypothyroidism. Supportive care is required if an overdose occurs.
Store at room temperature.
Let others know your experience or advice regarding this medication.
This medication has not been reviewed by a veterinarian yet.