Medication reference facts with explicit FDA-approval, off-label, source-limited, and safety context. Roxee does not sell, prescribe, or dispense medications.
BothReference completeFDA data linkedRx requiredLiquid (Suspension)Intervet, Inc.
Official label facts
Owner quick guide first
Merged from the current Roxee medication system with field-level provenance, freshness, and completeness tracking.
Prednisone
Corticosteroid used for inflammatory and immune-mediated conditions. Species commonly shown: Both, Dog, Restricted During Pregnancy, Horse, Restricted During Pregnancy.
Generic name
Prednisone
Brand names
Meticorten®
Manufacturer
Intervet, Inc.
Species
Both, Dog, Horse, Cat
Dosage forms
Liquid (Suspension)
Prescription
Prescription required
Completeness
100%
Validation
Complete
Brand names
Meticorten®
Dosage forms
Liquid (Suspension)
Indications / Uses
Corticosteroid used for inflammatory and immune-mediated conditions.
Administration / How To Give
Oral
Storage
Store at room temperature.
Warnings / Contraindications
Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history.
Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history.
Side Effects
Increased thirst/urination, increased appetite, panting, GI upset. Long-term use: immune suppression and other risks.
FAQ
Both, Dog, Restricted During Pregnancy, Horse, Restricted During Pregnancy, Horse, Not For Meat Production, Cat, Restricted During Pregnancy
A source-aware map of what to know, what is uncertain, and what to verify with your veterinarian.
Source Backed Signals
What to know
Evidence-backed contextLimited
Roxee has limited cited overview evidence for Prednisone; use the official documents and your veterinarian's instructions for product-specific decisions.
Source: openFDA case USA-USFDACVM-2026-US-014449
Safety signal coverageReported signals
32 tracked reaction signals; 32 reported cases; 19 serious reports; 2 species groups. These are reporting and label-derived signals for interpretation with a veterinarian.
Source: openFDA case USA-USFDACVM-2026-US-014449
Interpretation guardrailNot causation
Adverse-event reports help form a watch list, but they do not prove the medication caused the reaction and they are not a risk ranking between medications.
Evidence tension
Stronger signalLabel / review
Official labels, package inserts, and reviewed summaries carry more weight than isolated reports.
Source: openFDA case USA-USFDACVM-2026-US-014449
Weaker signalReported data
Case reports and openFDA terms are useful for pattern awareness, but they are incomplete, can include multiple exposures, and do not estimate an individual pet's probability of harm.
Reaction signal map
Most reported reactionsTop terms
Unsteady walking (ataxia) (1 reports), Loss of appetite (1 reports), Blood in urine (1 reports), Blood in faeces (1 reports), Aspiration pneumonia (1 reports)
Schnauzer - Miniature (1), Chihuahua (1), ['Shepherd Dog - Australian', 'Dog (unknown)'] (1), Retriever - Labrador (1). These are report metadata, not proof that a breed is at higher risk.
What your vet may verify
Fit for this patientVet check
Verify whether Prednisone fits the pet's species, current diagnosis, age, weight, organ status, pregnancy/lactation status, and concurrent medications.
Evidence limitationsEvidence review
Separate label-backed warnings from adverse-event reports and owner observations before changing the plan.
What to watch next
Watch listOwner-safe
Avoid combining with NSAIDs, Use caution with diabetes, infections, GI ulcer history, wobbly/unsteady walking, Loss of appetite, Blood in urine
Call sooner ifEscalation
Repeated vomiting or diarrhea. Severe lethargy (hard to wake, very low energy). Collapse or fainting.
Bottom line: Use this Prednisone brief as a structured watch list and source map, not as a reason to start, stop, or change treatment without your veterinarian.
LamenessWobblinessLethargy (see also Central nervous system depression in Neurological)Unable to walkWeaknessFeverImmune-mediated polyarthritisGastritisAbdominal cavity disorder NOSAbnormal ultrasound findingHyperproteinaemiaLymphopeniaEosinopeniaMedication error NOS
Body systems
OtherNeurologic
Outcomes
Ongoing
USA-USFDACVM-2026-US-012782
Received 2026-03-17
· MSK
· MSK
Serious
Species
Dog
Breed
Setter - English
Size / weight
25-49 lb (21.772 Kilogram)
Age
8+ years (9 Year)
Sex
Male Neutered
Region
USA
Reactions
Dilated renal pelvisIntestinal thickeningAbnormal ultrasound findingBradycardiaPale mucous membraneDiarrhoeaWeight lossLethargy (see also Central nervous system depression in Neurological)LymphomaMedication error NOS
Body systems
OtherDigestiveNeurologic
Outcomes
Ongoing
USA-USFDACVM-2026-US-011996
Received 2026-03-13
· MSK
· MSK
Serious
Species
Dog
Breed
Terrier - Bull - American Pit
Size / weight
50-99 lb (29.937 Kilogram)
Age
4-7 years (5 Year)
Sex
Male Neutered
Region
USA
Reactions
Injection site painAnorexiaFeverInjection site swellingInjection site abscessLethargy (see also Central nervous system depression in Neurological)
Body systems
OtherDigestiveSkin & allergyNeurologic
Outcomes
Ongoing
USA-USFDACVM-2026-US-009056
Received 2026-02-26
· MSK
· MSK
Serious
Species
Dog
Breed
Terrier - Bull - American Pit
Size / weight
50-99 lb (28.49 Kilogram)
Age
8+ years (8.42 Year)
Sex
Female Unknown
Region
USA
Reactions
Weight lossLethargy (see also Central nervous system depression in Neurological)Limb weakness
Body systems
OtherNeurologic
Outcomes
Ongoing
USA-USFDACVM-2026-US-006203
Received 2026-02-10
· MSK
· MSK
Serious
Species
Dog
Breed
Mountain Dog - Bernese
Size / weight
50-99 lb (35.698 Kilogram)
Age
4-7 years (7 Year)
Sex
Female Unknown
Region
USA
Reactions
Lethargy (see also Central nervous system depression in Neurological)InappetenceSwollen lip (see also Skin)Localised pain NOS (see other SOCs for specific pain)Ocular dischargeNot drinkingSmelly breathLip smackingWalking difficultyAbdominal painDrooping eyelidReluctant to moveOral ulcerationTongue ulcerationIntentional misuse
Body systems
NeurologicOther
Outcomes
Ongoing
USA-USFDACVM-2026-US-005003
Received 2026-02-04
· MSK
· MSK
Serious
Species
Dog
Breed
Rottweiler
Size / weight
50-99 lb (4 Kilogram)
Age
8+ years (1 Year)
Sex
Female Unknown
Region
USA
Reactions
Addison's diseaseLethargy (see also Central nervous system depression in Neurological)FebrileDecreased pulse oxygenationAspiration pneumoniaHypotensionElevated lactateHind limb paresisReduced reflexesDeath
Body systems
OtherNeurologic
Outcomes
Died
USA-USFDACVM-2025-US-074895
Received 2025-12-19
· MSK
· MSK
Serious
Species
Dog
Breed
Bloodhound
Size / weight
50-99 lb (41.28 Kilogram)
Age
4-7 years (5 Year)
Sex
Female Neutered
Region
USA
Reactions
Lethargy (see also Central nervous system depression in Neurological)Stiffness NOSWalking difficultyGeneralised weaknessNeutropeniaLow platelet countPain NOSDecreased appetiteVomitingElevated liver enzymes NOSFluid in abdomen NOSLiver disorder NOSOther immune system disorder NOSFeverLeucopenia NOSDistension of abdomenHypoglycaemiaAnaemia NOSIndigestion
Body systems
NeurologicOtherDigestive
Outcomes
Ongoing
USA-USFDACVM-2025-US-074897
Received 2025-12-12
· MSK
· MSK
Serious
Species
Dog
Breed
['Chihuahua', 'Dog (unknown)']
Size / weight
Under 10 lb (2.26 Kilogram)
Age
Under 1 year (2 Week)
Sex
Female Intact
Region
USA
Reactions
IcterusDeathOther abnormal test result NOSElevated liver enzymes NOSSwollen jointLocalised hair lossSkin lesion NOSConjunctival oedemaCorneal oedemaSkin scabSwollen limbLethargy (see also Central nervous system depression in Neurological)AnorexiaEar infection NOSLocal swelling (not application site)
Body systems
OtherSkin & allergyNeurologicDigestive
Outcomes
Died
USA-USFDACVM-2025-US-074521
Received 2025-12-11
· MSK
· MSK
Serious
Species
Cat
Breed
Domestic Longhair
Size / weight
10-24 lb (6.4 Kilogram)
Age
4-7 years (6 Year)
Sex
Male Neutered
Region
USA
Reactions
Lethargy (see also Central nervous system depression in Neurological)TremorAtaxiaLaboured breathingAgonal breathingLateral recumbencyShallow breathingAbnormal menace reflex testAbnormal pupil light reflexHead tilt - neurological disorder (see also Head tilt - ear disorder)Other abnormal test result NOS
Body systems
NeurologicOther
Outcomes
Ongoing
USA-USFDACVM-2025-US-072814
Received 2025-12-10
· MSK
· MSK
Serious
Species
Dog
Breed
Pinscher - Miniature
Size / weight
Under 10 lb (4.037 Kilogram)
Age
8+ years (1 Year)
Sex
Female Unknown
Region
USA
Reactions
Lethargy (see also Central nervous system depression in Neurological)TremblingLimpingHead downWalking difficultyFeverLack of efficacy - NOSElevated globulinsBlood in urineImmune-mediated polyarthropathyElevated protein:creatinine ratioProteinuriaIntentional misuse
Body systems
NeurologicOtherEffectiveness
Outcomes
Ongoing
USA-USFDACVM-2025-US-072289
Received 2025-12-08
· MSK
· MSK
Non-serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
Under 10 lb (3.62 Kilogram)
Age
4-7 years (7 Year)
Sex
Female Neutered
Region
USA
Reactions
UnwellWeight lossLethargy (see also Central nervous system depression in Neurological)HypoglycaemiaNot eating
Body systems
OtherNeurologic
Outcomes
Outcome Unknown
USA-USFDACVM-2025-US-071839
Received 2025-11-28
· MSK
· MSK
Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
10-24 lb (7.257 Kilogram)
Age
1-3 years (2 Year)
Sex
Male Neutered
Region
USA
Reactions
Lethargy (see also Central nervous system depression in Neurological)Stumbling gaitNot eatingNot drinkingCold feeling to the touchWobblinessNot urinatingUncomfortableFeverWeak pulseStiffness limbDecreased haematocritDecreased haemoglobinDecreased mean corpuscular volume (MCV)Decreased mean corpuscular haemoglobin concentration (MCHC)Red blood cell disorderHyperglycaemiaLow blood urea nitrogen (BUN)Low pancreatic enzymesUnable to walkEosinopenia
Body systems
NeurologicOther
Outcomes
Ongoing
USA-USFDACVM-2025-US-074320
Received 2025-11-24
· MSK
· MSK
Serious
Species
Dog
Breed
['Terrier (unspecified)', 'Dog (unknown)']
Size / weight
25-49 lb (18.14 Kilogram)
Age
8+ years (9 Year)
Sex
Male Neutered
Region
USA
Reactions
Behavioural disorder NOSEpidermal collaretteHepatic toxicosisDermal thickeningPyodermaJoint swellingLocal swelling (not application site)Skin ulcerLethargy (see also Central nervous system depression in Neurological)ItchingHair loss NOSDeathInappetence
Body systems
BehaviorOtherSkin & allergyNeurologic
Outcomes
Died
USA-USFDACVM-2025-US-068424
Received 2025-11-17
· MSK
· MSK
Serious
Species
Dog
Breed
['Terrier (unspecified)', 'Dog (unknown)']
Size / weight
25-49 lb (18.14 Kilogram)
Age
8+ years (9 Year)
Sex
Male Neutered
Region
USA
Reactions
Behavioural disorder NOSEpidermal collaretteHepatic toxicosisDermal thickeningPyodermaJoint swellingLocal swelling (not application site)Skin ulcerLethargy (see also Central nervous system depression in Neurological)ItchingHair loss NOSDeathInappetence
Body systems
BehaviorOtherSkin & allergyNeurologic
Outcomes
Died
USA-USFDACVM-2025-US-069207
Received 2025-11-13
· MSK
· MSK
Serious
Species
Cat
Breed
Domestic Shorthair
Size / weight
10-24 lb (5.5 Kilogram)
Age
8+ years (13 Year)
Sex
Female Unknown
Region
USA
Reactions
Elevated creatine-kinase (CK)AtaxiaStiffness limbUnable to standNot eatingWeight lossLethargy (see also Central nervous system depression in Neurological)Lying downUncomfortableAbnormal cytologyIntentional misuse
Body systems
OtherNeurologic
Outcomes
Ongoing
USA-USFDACVM-2025-US-065982
Received 2025-11-03
· MSK
· MSK
Serious
Species
Dog
Breed
Dachshund (unspecified)
Size / weight
10-24 lb (9.344 Kilogram)
Age
8+ years (14 Year)
Sex
Male Neutered
Region
USA
Reactions
Lethargy (see also Central nervous system depression in Neurological)AnorexiaPale mucous membraneDecreased haematocritThrombocytopeniaImmune mediated haemolytic anaemiaHyperthermiaHeavy breathingFluid in abdomen NOSWeight lossIntentional misuse
Body systems
NeurologicDigestiveOther
Outcomes
Ongoing
Tap or hover a reaction to see what it means in plain language.
Tracked signals
32
Reported cases
32
Serious reports
19
Species represented
2
Grouped by Body System
Digestive (2)
· Loss of appetite, Appetite disorder NOS
Skin & allergy (3)
· Hair loss, Application site hair loss, Alopecia local
Neurologic (1)
· Unsteady walking (ataxia)
Behavior (2)
· Behavioral disorder (unspecified), Anxiety
Other (24)
· Blood in urine, Blood in faeces, Blepharitis
Rendered from Roxee's cached FDA SPL package contents for on-page reading. Use Open original for the raw FDA ZIP/XML source.
Sponsor
Intervet, Inc.
NADA
9963
Status
RX
Form
Liquid (Suspension)
Route
Intramuscular
Species
Dog • Horse • Cat
Composition / specifications
Each milliliter of sterile aqueous suspension contains 10 to 40 milligrams of prednisone.
Horses
Indication
It is used for conditions requiring an anti-inflammatory agent.
Dosage
100 to 400 milligrams intramuscularly, repeating if necessary. If no response is observed after 3 to 4 days of therapy, reevaluate diagnosis.
Limitations
Do not use in viral infections. Except in emergency therapy, do not use in animals with tuberculosis, chronic nephritis, or Cushings's disease. With infections, use appropriate antibacterial therapy with and for at least 3 days after discontinuance of use and disappearance of all signs of infection. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta and metritis. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Dogs
Indication
It is used for conditions requiring an anti-inflammatory agent.
Dosage
0.25 to 1.0 milligram per pound of body weight for 3 to 5 days or until a response is noted. Treatment may be continued with an orally administered dose.
Limitations
Do not use in viral infections. Except in emergency therapy, do not use in animals with tuberculosis, chronic nephritis, or Cushings's disease. With infections, use appropriate antibacterial therapy with and for at least 3 days after discontinuance of use and disappearance of all signs of infection. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta and metritis. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Cats
Indication
It is used for conditions requiring an anti-inflammatory agent.
Dosage
0.25 to 1.0 milligram per pound of body weight for 3 to 5 days or until a response is noted. Treatment may be continued with an orally administered dose.
Limitations
Do not use in viral infections. Except in emergency therapy, do not use in animals with tuberculosis, chronic nephritis, or Cushings's disease. With infections, use appropriate antibacterial therapy with and for at least 3 days after discontinuance of use and disappearance of all signs of infection. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta and metritis. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Diagnosis-code mappings are not available for this medication yet.
Counseling and Monitoring Highlights
Global Pet owner/Vet mode is controlled in the header. This section avoids duplicate in-page persona tabs.
Owner-facing counseling points
Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history. (Contraindication, High)
Top reaction signals
Unsteady walking (ataxia) (1)Loss of appetite (1)Blood in urine (1)Blood in faeces (1)Aspiration pneumonia (1)Application site dry skin (1)Anaphylaxis (1)Anaemia NOS (1)
Identifiers & Packages
Normalized identifiers (NDC/NADA/ANADA) and package metadata from regulator listings.
Identifiers
NADA: 9963
Data Sources & Change Log
Every non-trivial field is expected to include provenance and update timestamps.
Official 8Clinical 4Manufacturer 0Marketing 0
Current Field Facts
side_effects: Increased thirst/urination, increased appetite, panting, GI upset. Long-term use: immune suppression and other risks. (Clinical, 2026-04-11)
storage_handling: Store at room temperature. (Clinical, 2026-04-12)
storage_handling: Store at room temperature. (Clinical, 2026-04-11)
storage_handling: Store at room temperature. (Clinical, 2026-02-12)
contraindications: Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history. (Official, 2026-04-12)
contraindications: Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history. (Official, 2026-04-11)
contraindications: Avoid combining with NSAIDs. Use caution with diabetes, infections, GI ulcer history. (Official, 2026-02-12)
side_effects: Increased thirst/urination, increased appetite, panting, GI upset. Long-term use: immune suppression and other risks. (Official, 2026-04-12)
side_effects: Increased thirst/urination, increased appetite, panting, GI upset. Long-term use: immune suppression and other risks. (Official, 2026-02-12)
usage: Corticosteroid used for inflammatory and immune-mediated conditions. (Official, 2026-04-12)
usage: Corticosteroid used for inflammatory and immune-mediated conditions. (Official, 2026-04-11)
usage: Corticosteroid used for inflammatory and immune-mediated conditions. (Official, 2026-02-12)
Recent Revisions
side_effects updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
contraindications updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
usage updated 2026-04-12 10:05 by etl_backfill • Backfilled from existing medication fields
side_effects updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
contraindications updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
usage updated 2026-04-11 10:05 by etl_backfill • Backfilled from existing medication fields
side_effects updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
contraindications updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
usage updated 2026-02-12 19:40 by etl_backfill • Backfilled from existing medication fields
FDA Products & Applications (Animal Drugs @ FDA)
Official sponsor/proprietary-name/application-status records linked by active ingredient.
Data source: FDA Animal Drugs @ FDA (public search export).
What It's For (FDA Label Highlights)
Extracted from FDA Animal Drugs @ FDA product labeling. Always confirm details with your veterinarian.
Species: Dog • Horse • Cat
Composition / specifications
Each milliliter of sterile aqueous suspension contains 10 to 40 milligrams of prednisone.
Horses
Indication
It is used for conditions requiring an anti-inflammatory agent.
Dosage
100 to 400 milligrams intramuscularly, repeating if necessary. If no response is observed after 3 to 4 days of therapy, reevaluate diagnosis.
Limitations
Do not use in viral infections. Except in emergency therapy, do not use in animals with tuberculosis, chronic nephritis, or Cushings's disease. With infections, use appropriate antibacterial therapy with and for at least 3 days after discontinuance of use and disappearance of all signs of infection. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta and metritis. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Dogs
Indication
It is used for conditions requiring an anti-inflammatory agent.
Dosage
0.25 to 1.0 milligram per pound of body weight for 3 to 5 days or until a response is noted. Treatment may be continued with an orally administered dose.
Limitations
Do not use in viral infections. Except in emergency therapy, do not use in animals with tuberculosis, chronic nephritis, or Cushings's disease. With infections, use appropriate antibacterial therapy with and for at least 3 days after discontinuance of use and disappearance of all signs of infection. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta and metritis. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Cats
Indication
It is used for conditions requiring an anti-inflammatory agent.
Dosage
0.25 to 1.0 milligram per pound of body weight for 3 to 5 days or until a response is noted. Treatment may be continued with an orally administered dose.
Limitations
Do not use in viral infections. Except in emergency therapy, do not use in animals with tuberculosis, chronic nephritis, or Cushings's disease. With infections, use appropriate antibacterial therapy with and for at least 3 days after discontinuance of use and disappearance of all signs of infection. Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta and metritis. Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian.
Partial lack of efficacySkin lesion NOSInappropriate elimination NOSPolyuriaPolydipsiaMedication error NOSLickingAbnormal histology NOS
Outcomes: Ongoing
Data source: FDA openFDA Animal & Veterinary adverse event reports.
Overdose Information
No approved overdose-management text is linked yet. If overdose is suspected, contact a veterinarian or emergency clinic immediately.
Storage & Handling
Store at room temperature.
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This medication has not been reviewed by a veterinarian yet.
Medical Disclaimer: The medication details provided on Roxee are for informational purposes only and are not a substitute for professional veterinary advice. Always consult your veterinarian about your pet's specific needs.