Pet Medication Guide

Both Non-Rx Known brand: CAPSTAR®

Nitenpyram

For the treatment of flea infestations. The concurrent use of flavored milbemycin oxime and lufenuron tablets with nitenpyram tablets is indicated to kill adult fleas and prevent flea eggs from hatching. In ca…

Generic ingredient Care category: Flea & Tick Reference complete Tablet FDA branded products available 100% reference complete

Manufacturer Multiple FDA labelers

FDA products 15 FDA products linked

Brand names 5 brand names linked

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Lack of efficacy (ectoparasite) - flea Panting Diarrhea

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

SIMPARICA® Simparica Chewables

Both Rx required Known brand: SIMPARICA®

Sarolaner

SIMPARICA® kills adult fleas, and is indicated for the treatment and prevention of flea infestations ( Ctenocephalides felis ), and the treatment and control of tick infestations [ Amblyomma americanum (lone s…

Generic ingredient Care category: Flea & Tick Reference complete Chewable Tablets FDA branded products available 100% reference complete

Manufacturer Zoetis Inc.

FDA products 18 FDA products linked

Brand names 2 brand names linked

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Vomiting Seizure NOS Overdose

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

Revolution® Selarid®

Both Rx required Known brand: Revolution®

Selamectin

Revolution kills adult fleas and prevents flea eggs from hatching for one month and is indicated for the preventionand control of flea infestations ( Ctenocephalides felis ), prevention of heartworm disease ca…

Generic ingredient Care category: Flea & Tick Reference complete Liquid FDA branded products available 100% reference complete

Manufacturer Multiple FDA labelers

FDA products 67 FDA products linked

Brand names 11 brand names linked

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Vomiting Lack of efficacy (ectoparasite) - flea Intentional misuse

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

Comfortis® Comfortis

Both Rx required Known brand: Comfortis®

Spinosad

To kill fleas and for the prevention and treatment of flea infestations ( Ctenocephalides felis ) for 1 month on dogs and puppies 14 weeks of age and older and 5.0 pounds or body weight or greater. To kill fle…

Generic ingredient Care category: Flea & Tick Reference complete Tablet (Chewable) FDA branded products available 100% reference complete

Manufacturer Elanco US Inc.

FDA products 10 FDA products linked

Brand names 2 brand names linked

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Vomiting Lack of efficacy (endoparasite) - heartworm Death

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

Care category

Antibiotics

Antibacterial medications used for common bacterial infections.

Grouped results

Clavacillin® Amoxicillin and Clavulanate Potassium Tablets

Both Rx required Known brand: Clavacillin®

Amoxicillin-Clavulanate

Antibiotic combination used for susceptible bacterial infections (often skin, soft tissue, dental, urinary). Species commonly shown: Both, Dog, No Use Class Stated Or Implied, Cat, No Use Class Stated Or Impli…

Generic ingredient Care category: Antibiotics Reference complete Drops FDA branded products available 100% reference complete

Manufacturer Multiple FDA labelers

FDA products 21 FDA products linked

Brand names 10 brand names linked

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Vomiting Abnormal cytology Local swelling (not application site)

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

Convenia® Cefovecin Sodium for Injection

Both Rx required Known brand: Convenia®

Cefovecin

For the treatment of skin infections (wounds and abscesses) in cats caused by susceptible strains of Pasteurella multocida . For the treatment of skin infections (secondary superficial pyoderma, abscesses, and…

Generic ingredient Care category: Antibiotics Reference complete Powder No FDA branded products linked 100% reference complete

Manufacturer Multiple FDA sponsors

FDA products No FDA products linked

Brand names 2 brand names linked

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Emesis (multiple) Fever Itching

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

Rilexine® RILEXINE

Both Rx required Known brand: Rilexine®

Cephalexin

Cephalosporin antibiotic used for susceptible bacterial infections (often skin/soft tissue). Species commonly shown: Both, Dog, No Use Class Stated Or Implied.

Generic ingredient Care category: Antibiotics Reference complete Chewable Tablets FDA branded products available 100% reference complete

Manufacturer Multiple FDA labelers

FDA products 6 FDA products linked

Brand names 3 brand names linked

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Lack of efficacy - NOS Diarrhea Abnormal movement NOS

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

Baytril™ Antibacterial Tablets Baytril™ Taste Tabs™ Antibacterial Tablets Baytril™ Antibacterial Injectable Solution

Both Rx required Known brand: Baytril™ Antibacterial Tablets Baytril™ Taste Tabs™ Antibacterial Tablets

Enrofloxacin

Fluoroquinolone antibiotic used for susceptible bacterial infections. Species commonly shown: Both, Dog, No Use Class Stated Or Implied, Cat, No Use Class Stated Or Implied.

Generic ingredient Care category: Antibiotics Reference complete Tablet FDA branded products available 100% reference complete Video

Manufacturer Multiple FDA labelers

FDA products 113 FDA products linked

Brand names 37 brand names linked

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Fever Abnormal radiograph finding Loss of appetite

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

Heartgard® Plus Tri-Heart Plus Chewable Tablets

Both Rx required Known brand: Heartgard® Plus

Ivermectin, Pyrantel

To prevent canine heartworm diseases by eliminating the tissue stage of heartworm larvae ( Dirofilaria immitis ) for a month (30 days) after infection. For the treatment and control of ascarids ( Toxocara cani…

Generic ingredient Care category: Antibiotics Reference complete Tablet (Chewable) No FDA branded products linked 100% reference complete

Manufacturer Multiple FDA labelers

FDA products No FDA products linked

Brand names 2 brand names linked

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Drooling Vomiting Lack of efficacy (endoparasite) - heartworm

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

DIROBAN®

Both Rx required Known brand: DIROBAN®

Melarsomine Dihydrochloride

Treatment of stabilized, class 1, 2, and 3 heartworm disease (asymptomatic to mild, moderate, and severe, respectively) caused by immature (4 month-old, stage L5) to mature adult infections of Dirofilaria immi…

Generic ingredient Care category: Antibiotics Reference complete Powder No FDA branded products linked 100% reference complete

Manufacturer Anzac Animal Health, LLC

FDA products No FDA products linked

Brand names 1 brand name linked

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Vomiting Drooling Lack of efficacy (endoparasite) - heartworm

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

AYRADIA™ AYRADIA

Both Rx required Known brand: AYRADIA™

Metronidazole

Antibiotic/antiprotozoal used for certain GI infections and inflammation. Species commonly shown: Both, Dog, No Use Class Stated Or Implied.

Generic ingredient Care category: Antibiotics Reference complete Suspension FDA branded products available 100% reference complete

Manufacturer Multiple FDA labelers

FDA products 11 FDA products linked

Brand names 5 brand names linked

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Vomiting Diarrhea Lack of efficacy - NOS

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

ProHeart™ Quest® Gel

Both Rx required Known brand: ProHeart™

Moxidectin

To prevent infection by the canine heartworm Dirofilaria immitis and the subsequent development of canine heartworm disease. For the treatment and control of the following stages of gastrointestinal parasites …

Generic ingredient Care category: Antibiotics Reference complete Tablet FDA branded products available 100% reference complete

Manufacturer Multiple FDA labelers

FDA products 23 FDA products linked

Brand names 19 brand names linked

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Vomiting Lack of efficacy (endoparasite) - heartworm Lack of efficacy (endoparasite) - hookworm

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

Dog Wormer Tablets Dog Wormer Chewable Tablets D-Worm™ Adams™

Both Rx required Known brand: Dog Wormer Tablets

Pyrantel

For the removal and control of infections from the following mature parasites: Large strongyles ( Strongylus vulgaris , Strongylus edentatus , Strongylus equinus ), small strongyles, pinworms ( Oxyuris equi ) …

Generic ingredient Care category: Antibiotics Reference complete Tablet No FDA branded products linked 100% reference complete

Manufacturer Multiple FDA sponsors

FDA products No FDA products linked

Brand names 15 brand names linked

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Vomiting Drooling Lack of efficacy (endoparasite) - hookworm

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

Dog Wormer Tablets Dog Wormer Chewable Tablets D-Worm™ Adams™

Both Rx required Known brand: Dog Wormer Tablets

Pyrantel As Pamoate Salt

Generic ingredient Care category: Antibiotics Reference complete Sources vary Suspension No FDA branded products linked 100% reference complete

Manufacturer Multiple FDA labelers

FDA products No FDA products linked

Brand names 15 brand names linked

Source variance noted Roxee found source differences in non-clinical fields such as brand, manufacturer, source URL, or display metadata. Core owner guidance and official source links are sti…

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Vomiting Tiredness (lethargy) Lack of efficacy (endoparasite) - hookworm

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

Dog Wormer Tablets Dog Wormer Chewable Tablets D-Worm™ Adams™

Both Rx required Known brand: Dog Wormer Tablets

Pyrantel Pamoate

Generic ingredient Care category: Antibiotics Reference complete Tablet No FDA branded products linked 100% reference complete

Manufacturer Multiple FDA sponsors

FDA products No FDA products linked

Brand names 15 brand names linked

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Emesis (multiple) Lack of efficacy (endoparasite) - hookworm Death

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

Care category

Heart

Cardiac support therapies and heartworm-related medication classes.

Grouped results

Salix® Salix® Tablets

Both Rx required Known brand: Salix®

Furosemide

Diuretic used to manage fluid overload (commonly in heart failure). Species commonly shown: Both, Dog, No Use Class Stated Or Implied, Horse, Not For Meat Production.

Generic ingredient Care category: Heart Reference complete Liquid (Solution) FDA branded products available 100% reference complete

Manufacturer Multiple FDA labelers

FDA products 21 FDA products linked

Brand names 14 brand names linked

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Cough Death by euthanasia Death

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

Ivomec® 1% Injection Ivomec® .27% Injection Grower And Feeder Pigs Ivomec® Injection for Cattle Ivomec® 1% Injection for Cattle And Swine Ivomec® Liquid

Both Rx required Known brand: Ivomec® 1% Injection Ivomec® .27% Injection Grower And Feeder Pigs Ivomec® Injection for Cattle Ivomec® 1% Injection for Cattle And Swine

Ivermectin

Used monthly for heartworm prevention in dogs and cats; also controls certain intestinal parasites. Species commonly shown: Both, Fox, Ranch, Bison, American.

Generic ingredient Care category: Heart Reference complete Liquid (Solution) FDA branded products available 100% reference complete

Manufacturer Multiple FDA labelers

FDA products 151 FDA products linked

Brand names 63 brand names linked

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Vomiting Drooling Lack of efficacy (endoparasite) - roundworm NOS

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

Dog Rx required

Vetmedin® Vetmedin® Solution

Dog Rx required Known brand: Vetmedin®

Pimobendan

Inodilator used for certain forms of canine heart failure (e.g., myxomatous mitral valve disease, dilated cardiomyopathy). Species commonly shown: Dog, Dog, No Use Class Stated Or Implied.

Generic ingredient Care category: Heart Reference complete Solution FDA branded products available 100% reference complete

Manufacturer Multiple FDA labelers

FDA products 68 FDA products linked

Brand names 9 brand names linked

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Vomiting Elevated blood urea nitrogen (BUN) Loss of appetite

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

Care category

GI

Digestive and gastrointestinal support medications.

Grouped results

Both

Incomplete

Famotidine

Both

Acid-reducing medication used for GI upset and reflux. Species commonly shown: Both.

Generic ingredient Care category: GI Source review pending Source coverage pending Source coverage pending 85% reference complete

Approval status Source coverage pending

Disclosure Roxee has limited supporting content for this record, but no on-page official FDA animal-drug document is linked yet. Treat it as source-limited unti…

Warnings Highlighted

Source review pending Source review pending

Safety snapshot Source-backed adverse-effect snapshot

Vomiting Elevated blood urea nitrogen (BUN) Loss of appetite

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

Cerenia® Tablets Cerenia® Injectable Solution

Both Rx required Known brand: Cerenia® Tablets

Maropitant Citrate

Antiemetic used to prevent and treat vomiting (and motion sickness in dogs). Species commonly shown: Both, Dog, No Use Class Stated Or Implied, Cat, No Use Class Stated Or Implied.

Generic ingredient Care category: GI Reference complete Tablet No FDA branded products linked 100% reference complete

Manufacturer Multiple FDA sponsors

FDA products No FDA products linked

Brand names 4 brand names linked

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Vomiting Fever Drooling

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

GastroGard® UlcerGard®

Both Rx required Known brand: GastroGard®

Omeprazole

Proton pump inhibitor used to reduce stomach acid (ulcers, reflux). Species commonly shown: Both, Horse, Not For Meat Production, Horse, Foals 4 Weeks And Older, Not For Food.

Generic ingredient Care category: GI Reference complete Paste FDA branded products available 100% reference complete

Manufacturer Multiple FDA labelers

FDA products 17 FDA products linked

Brand names 10 brand names linked

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Emesis (multiple) Dehydration Death by euthanasia

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

Droncit™ 5.68% Injectible Solution Droncit® Feline Cestocide Tablets Praziquantel 34 (Rx) Droncit® Canine Cestocide Tablets Tapeworm Dewormer for Dogs (OTC) Tapeworm Dewormer for Cats (OTC)

Both Rx required Known brand: Droncit™ 5.68% Injectible Solution

Praziquantel

For removal of canine cestodes: Dipylidium caninum, Taenia pisiformis, and Echinococcus granulosus, and removal and control of canine cestode Echinococcus multilocularis. For removal of feline cestodes Dipylid…

Generic ingredient Care category: GI Reference complete Tablet FDA branded products available 100% reference complete

Manufacturer Multiple FDA labelers

FDA products 40 FDA products linked

Brand names 20 brand names linked

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Vomiting Diarrhea Lack of efficacy (endoparasite) - tapeworm

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

Dog Rx required

VETORYL® CAPSULES Vetoryl

Dog Rx required Known brand: VETORYL® CAPSULES

Trilostane

Used to treat hyperadrenocorticism (Cushing’s disease) in dogs by inhibiting cortisol production. Requires regular monitoring via ACTH stimulation tests and electrolyte checks. Species commonly shown: Dog, Dog…

Generic ingredient Care category: GI Reference complete Capsule FDA branded products available 100% reference complete

Manufacturer Multiple FDA labelers

FDA products 51 FDA products linked

Brand names 5 brand names linked

Warnings Highlighted

Reference refreshed Jun 21, 2026

Safety snapshot Source-backed adverse-effect snapshot

Vomiting Elevated serum alkaline phosphatase Diarrhea

These are reported or curated adverse-effect terms. They do not prove causality, are not frequency estimates, and should not be used to compare medication risk.

Care category

Deworming

Anthelmintic treatments for intestinal parasite control.

Grouped results

FIDOQUEL™-CA1 FIDOQUEL-CA1